Details of Factor

General Information of Factor (ID: FP132)
  Factor Name Biomalt Solid Agar Medium
  Factor Type Environmental Conditions
  Factor Description
Each microbial strain has the potential to produce multiple compounds, but only subsets of these compounds are made under specific growth conditions. Therefore, variations in cultivation parameters can elicit the production and discovery of new secondary metabolites by changing cultivation parameters such as media composition, various nutrients, trace elements, physical parameters (i.e., pH, temperature), and chemical elicitors (i.e., sub-lethal concentrations of antibiotics, communication molecules). Moreover, the co-cultivation of microbes and the addition of factors affecting epigenetic control can also be framed within the OSMAC principle.
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 The Content Variation of Natural Product Induced by This Factor
      Species Name: Colletotrichum sp. strain 6728
          Species Info Click to show the detail information of this Factor
          Experiment Detail
The endophytic fungus Seimatosporium sp. (internal strain no. 8883) was isolated from Salsola oppositifolia, from Gomera (Spain), and was cultivated on a biomalt solid agar medium (12 L, 5% (w/v)) at room temperature for 21 days.
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            Colletonoic Acid [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Prerow
NP Content: 5.5 mg
      Species Name: Coniothyrium sp. strain zw86
          Species Info Click to show the detail information of this Factor
          Experiment Detail
Plant material was collected in Yangling, Shaanxi province, China, in April 2011. All 28 isolated fungal strains (XC1-XC28) were fermented on solid rice medium. Toxicity of the fermented culture (20 µg/mL) against brine shrimp were assayed according to our previously reported protocol. The most toxic strain XC16 was selected to be cultivated on rice medium (40 g rice and 100 mL distilled water, sterilized under 121 °C for 30 min) in 200 Erlenmeyer flasks (500 mL each). The flask cultures were incubated under 28 °C for 3 weeks.
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            1,7-Dihydroxy-3-methylanthracene-9,10-dione [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 1 mg
            1-Hydroxy-3-Hydroxymethyl-9,10-Anthraquinone [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 3 mg
            9,10-Anthracenedione, 1-Hydroxy-3-Methyl- [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 1000 mg
            Coniothyrinone A [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 2 mg
            Coniothyrinone B [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 2 mg
            Coniothyrinone C [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 1.5 mg
            Coniothyrinone D [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 2 mg
            Phomarin [2]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 28Days)
    NP Info    NA Canary Islands, Gomera
NP Content: 1.3 mg
      Species Name: Seimatosporium sp. strain no. 8883
          Species Info Click to show the detail information of this Factor
          Experiment Detail
The endophytic fungus Seimatosporium sp. (internal strain no. 8883) was isolated from Salsola oppositifolia, from Gomera (Spain), and was cultivated on a biomalt solid agar medium (12 L, 5% (w/v)) at room temperature for 21 days.
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            (+)-Epoxydon monoacetate [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 21Days)
    NP Info    NA Gomera, Spain
NP Content: 4.5 mg
            2-Hydroxymethyl-4Beta,5Alpha,6Beta-Trihydroxycyclohex-2-Enone [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 21Days)
    NP Info    NA Gomera, Spain
NP Content: 10 mg
            Isoepoxydon [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 21Days)
    NP Info    NA Gomera, Spain
NP Content: 4 mg
            Phyllostine [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 21Days)
    NP Info    NA Gomera, Spain
NP Content: 3 mg
            Seimatoric Acid [1]
               Factor Link Part Location NP Content
 
Biomalt Solid Agar Medium (25 degrees Celsius + 21Days)
    NP Info    NA Gomera, Spain
NP Content: 1.5 mg

References
1 Seimatoric acid and colletonoic acid: Two new compounds from the endophytic fungi, Seimatosporium sp. and Colletotrichum sp.
2 Structural and stereochemical studies of hydroxyanthraquinone derivatives from the endophytic fungus Coniothyrium sp.