Details of Natural Product (NP)

General Information of Natural Product (ID: NP0967)
  Natural Product Name
Methionine
  Synonyms
L-methionine; 63-68-3; methionine; h-Met-oh; (S)-2-Amino-4-(methylthio)butanoic acid; Cymethion; L-(-)-Methionine; Liquimeth; S-Methionine; L-Methioninum; Methilanin; Neo-methidin; (L)-Methionine; Methionine (VAN); Acimethin; Metionina [DCIT]; L-Methionin; (S)-methionine; L-alpha-Amino-gamma-methylmercaptobutyric acid; h-Met-h; Methioninum [INN-Latin]; metionina; Methioninum; L-Homocysteine, S-methyl-; (2S)-2-amino-4-(methylsulfanyl)butanoic acid; METHIONINE, L-; L(-)-Amino-gamma-methylthiobutyric acid; L-alpha-Amino-gamma-methylthiobutyric acid; L-gamma-Methylthio-alpha-aminobutyric acid; met; CCRIS 5528; CCRIS 5536; HSDB 4317; 2-Amino-4-methylthiobutanoic acid (S)-; UNII-AE28F7PNPL; (S)-2-amino-4-(methylthio)butyric acid; 2-Amino-4-(methylthio)butyric acid, (S)-; (2S)-2-amino-4-methylsulfanyl-butanoic acid; L-Met; Butanoic acid, 2-amino-4-(methylthio)-, (S)-; Toxin WAR (Bacillus thuringiensis strain PS205C); L-a-Amino-g-methylthiobutyric acid; carbon-11 methionine; S-Methyl-L-homocysteine; (S)-(+)-Methionine; MFCD00063097; AE28F7PNPL; gamma-Methylthio-alpha-aminobutyric acid; L-2-Amino-4-(methylthio)butanoic acid; CHEMBL42336; (2S)-2-Amino-4-methylsulfanylbutanoic acid; CHEBI:16643; Poly-L-methionine; L-2-Amino-4methylthiobutyric acid; (S)-2-Amino-4-(methylmercapto)butyric acid; 58576-49-1; Polymethionine; Methionine [USAN:INN]; C-11 Methionine; l-2-Amino-4-(methylthio)butyric acid; EINECS 200-562-9; (2S)-2-amino-4-(methylsulfanyl)butanoate; NSC 22946; C-11 Met; NSC-22946; 3h-l-methionine; g-Methylthio-a-aminobutyric acid; racemic methionine; 1wkm; Methionine [USAN:USP:INN:BAN]; Toxin WAR; (35S)Methionine; 2-Amino-4-(methylthio)butyrate; Methionine (USP); L(-)-Methionin; a-Amino-g-methylmercaptobutyric acid; L-Methionine,(S); 1006386-95-3; L-S-methylhomocysteine; 1pg2; 1qq9; L-Methionine-[34S]; L-Methionine Z (TN); L-Methionine (JP17); Methionine (L-Methionine); Methionine, L- (8CI); bmse000044; bmse000915; SCHEMBL4226; G-methylthio-a-aminobutyrate; L-Methionine (H-Met-OH); H-Met-2-Chlorotrityl Resin; 2-Amino-4-methylthiobutanoate; L-a-amino-g-methylthiobutyrate; GTPL4814; A-amino-g-methylmercaptobutyrate; DTXSID5040548; SCHEMBL15702352; Pharmakon1600-01301006; alpha-amino-alpha-aminobutyric acid; gamma-methylthio-alpha-aminobutyrate; HY-N0326; L-Methionine, Cell Culture Reagent; ZINC1532529; L-2-Amino-4-methylthiobutyric acid; BDBM50142500; MFCD00801344; NSC760117; s5633; L-alpha-amino-gamma-methylthiobutyrate; L-Methionine, Vetec(TM), 98.5%; (S)-2-Amino-4-(methylthio)butanoate; AKOS000281626; AKOS015852512; L-Methionine, labeled with carbon-11; alpha-amino-gamma-methylmercaptobutyrate; CCG-266196; CS-W020566; DB00134; MCULE-7228063662; NSC-760117; (S)-2-amino-4-(methylthio)-Butanoate; NCGC00160620-01; NCGC00160620-02; AS-10898; (S)-2-amino-4-(methylthio)-Butanoic acid; DB-029971; L-Methionine, BioUltra, >=99.5% (NT); A5456; AM20100552; M0099; L-Methionine, SAJ special grade, >=98.5%; 63M683; C00073; D00019; D70895; L(-)-amino-alpha-amino-alpha-aminobutyric acid; L-Methionine, reagent grade, >=98% (HPLC); M-3100; M02939; M02945; L-Methionine, Vetec(TM) reagent grade, >=98%; A934626; C6CB5837-2B49-4B25-AAB0-D305DAFE26EB; Q22124685; F1905-8241; Z1250208671; L-Methionine, certified reference material, TraceCERT(R); Methionine, European Pharmacopoeia (EP) Reference Standard; UNII-0O72R8RF8A component FFEARJCKVFRZRR-BYPYZUCNSA-N; UNII-73JWT2K6T3 component FFEARJCKVFRZRR-BYPYZUCNSA-N; UNII-N7U7BXP2OI component FFEARJCKVFRZRR-BYPYZUCNSA-N; N-(2CT Resin)-L-Met-OH (200-400 mesh, > 0.3 mmol/g); L-Methionine, United States Pharmacopeia (USP) Reference Standard; L-Methionine, Pharmaceutical Secondary Standard; Certified Reference Material; Soft tissue sarcoma-associated protein (human clone WO2004048938-SEQID-1139); L-Methionine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%; L-Methionine, PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture
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  Formula C5H11NO2S
  Weight 149.21
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
  InChI Key FFEARJCKVFRZRR-BYPYZUCNSA-N
  Isomeric SMILES CSCC[C@@H](C(=O)O)N
  Canonical SMILES CSCCC(C(=O)O)N
  External Links PubChem ID 6137
CAS ID 59-51-8
CHEMBL ID CHEMBL42336
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Solanum lycopersicum cv. Micro-Tom
  Factor Name: Developmental Stage Variation; AMF Inoculation [1]
              Species Info Factor Info
               Experiment Detail
Solanum lycopersicum cv.Micro-Tom tomato seeds were sterilized with a series of washes: 3 min in 70% ethanol, to which 3-4 drops of tween 20 were added, 13 min in a 5% bleach solution and 3 washes of 10 min each in sterile water. The seeds were then placed in a 0.6% agar medium (5 seeds per petri dish). The petri dishes were kept for 5 days in the dark, followed by 4 days in the light. The germinating seedlings were then transferred to pots with sterile quartz sand. For mycorrhization, the fungus Glomus mosseae Gerd. & Trappe (BEG 12) was purchased from Biorize (Dijon, France). A mixture of sand (70%) and fungal inoculum (30%) was used. The mycorrhizal and control plants were grown in a growth chamber under a 14 h light (24&#8451)/10 h dark (20&#8451) regime, and watered, 125 ml/plant twice a week with water, and once a week with a modified Long-Ashton solution containing a low phosphorus concentration (3.2 µM Na2HPO4.12H2O). The fruit was collected when it reached the required ripening stage i.e. turning.
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               Factor Function
Mycorrhization accelerated the flowering and fruit development and increased the fruit yield. Eleven transcripts were differentially regulated in the fruit upon mycorrhization, and the mycorrhiza-responsive genes resulted to be involved in nitrogen and carbohydrate metabolism as well as in regulation and signal transduction. Mycorrhization has increased the amino acid abundance in the fruit from mycorrhizal plants, with glutamine and asparagine being the most responsive amino acids.
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               Factor Part Location NP Content
 
Fruit: Mature green stage
 Fruits NA
NP Content: 074 ± 17 nmol/mg dry weight
 
Fruit: (Mature green stage) + (Glomus mosseae inoculation)
 Fruits NA
NP Content: 104 ± 113 nmol/mg dry weight
 
Fruit: Turning stage
 Fruits NA
NP Content: 495 ± 0.359 nmol/mg dry weight
 
Fruit: (Turning stage) + (G. mosseae inoculation)
 Fruits NA
NP Content: 472 ± 0.085 nmol/mg dry weight
 
Fruit: Red stage
 Fruits NA
NP Content: 1800 ± 215 nmol/mg dry weight
 
Fruit: (Red stage) + (G. mosseae inoculation)
 Fruits NA
NP Content: 2024 ± 515 nmol/mg dry weight
References
1 The arbuscular mycorrhizal status has an impact on the transcriptome profile and amino acid composition of tomato fruit