General Information of Natural Product (ID: NP1155)
  Natural Product Name
Cyclocolorenone
  Synonyms
Cyclocolorenone; 489-45-2; DTXSID20964135; Q67879817; 1,1,4,7-Tetramethyl-1,1a,2,3,4,4a,5,7b-octahydro-6H-cyclopropa[e]azulen-6-one; 6H-Cycloprop(e)azulen-6-one, 1,1a,2,3,4,4a,5,7b-octahydro-1,1,4,7-tetramethyl-, (1aR-(1aalpha,4alpha,4abeta,7balpha))-
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  Formula C15H22O
  Weight 218.33
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C15H22O/c1-8-5-6-11-14(15(11,3)4)13-9(2)12(16)7-10(8)13/h8,10-11,14H,5-7H2,1-4H3/t8-,10-,11-,14-/m1/s1
  InChI Key ZEEUIOBUKGZKPS-IDTAVKCVSA-N
  Isomeric SMILES C[C@@H]1CC[C@@H]2[C@@H](C2(C)C)C3=C(C(=O)C[C@H]13)C
  Canonical SMILES CC1CCC2C(C2(C)C)C3=C(C(=O)CC13)C
  External Links PubChem ID 160491
CAS ID 489-45-2

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Talauma ovata
  Factor Name: Month Variation [1]
              Species Info Factor Info
               Experiment Detail
Talauma ovata was collected from October 2003 to February 2005. Leaves and trunk bark from the same set of plants were collected in the four seasons: spring (October 15th, 2003), autumn (April 10th, 2004), winter (July 17th, 2004) and summer (February 15th, 2005). In addition, trunk bark was also collected on January 22nd, 2004 (summer). The plant material was harvested from wild-growing population in Santos Dumont City, Minas Gerais State, Brazil, (21° 28′ 03″ S, 43° 39′ 26″ W), at 1000 m of altitude.
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               Factor Function
In each season the composition of trunk bark oils was similar to leaf oils, with mainly quantitative differences. However considerable seasonal variation was observed. Significant levels of monoterpenes were found only in autumn. The content of oxygenated sesquiterpenes was highest in samples of spring (October) and decreased in summer (January and February), reaching the lowest level in autumn (April) and increasing again in winter (July). In trunk bark oils the main constituents were: spathulenol, alpha-eudesmol, linalool, trans-beta-guaiene and caryophyllene oxide. The major component in all samples of trunk bark was spathulenol. Its level was highest in October (46.8%), decreased in January (33.3%), remained stable in April and July (18.0%) and increased again in February of next year (27.7%). Levels of alpha-eudesmol were high in spring (13.0%) and autumn (11.5%). Linalool peaked only in April, while trans-beta-guaiane peaked in July (11.1%). Caryophyllene oxide ranged between 10.7-2.0%. The level was highest in January, decreased regularly until July and increased slightly again in October. In leaf oils the main components were: spathulenol, germacrene B, germacrene D, caryophyllene oxide and viridiflorol. Spathulenol was the major component in sample of spring (34.4%), but decreased gradually until winter, when reached the lowest level (9.4%). Caryophyllene oxide showed a similar pattern, varying from 14.1% (spring) to 2.4% (winter). An inverse effect was observed for viridiflorol, which increased from 0.1% in October to 13.7% in July. Important levels of alpha-eudesmol were observed in October (12.3%) and February (9.5%). The percentage of germacrene D was highest in summer, while germacrene B showed high amounts in autumn and winter. The seasonal changes in oil composition of T. ovata can be associated with cycle of life of plant (flowering, fruiting and vegetative stages) and climatic parameters such as intense raining in the spring and summer.
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               Factor Part Location NP Content
 
Leaf: (Harvesting time: February)
Leaves Brazil
NP Content: 0.5 %
 
Leaf: (Harvesting time: October)
Leaves Brazil
NP Content: 0.1 %
 
Trunk Bark: (Harvesting time: January)
Trunk bark Brazil
NP Content: 6.3 %
 
Trunk Bark: (Harvesting time: February)
Trunk bark Brazil
NP Content: 0.5 %
 
Trunk Bark: (Harvesting time: April)
Trunk bark Brazil
NP Content: 2.1 %
 
Trunk Bark: (Harvesting time: July)
Trunk bark Brazil
NP Content: 1.4 %
 
Trunk Bark: (Harvesting time: October)
Trunk bark Brazil
NP Content: 1.8 %
References
1 Chemical Composition, Seasonal Variation and Evaluation of Antimicrobial Activity of Essential Oils of Talauma ovata A. St. Hil. (Magnoliaceae)