Details of Natural Product (NP)

General Information of Natural Product (ID: NP1454)
  Natural Product Name
Tabersonine
  Synonyms
Tabersonine; Tabersonin; 4429-63-4; UNII-MN955K48NB; MN955K48NB; CHEBI:16776; (-)-Tabersonine; Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)-; (5alpha,12beta,19alpha)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylic acid, methyl ester; methyl (5alpha,12beta,19alpha)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate; methyl 2,3,6,7-tetradehydro-5alpha,12beta,19alpha-aspidospermidine-3-carboxylate; EINECS 224-615-0; BRN 0050163; Devil's Claw Extract; 4-25-00-00997 (Beilstein Handbook Reference); SCHEMBL829379; AMY596; CHEMBL2011511; Tabersonine, >=95% (HPLC); DTXSID30196102; HMS3887M03; HY-N1431; MFCD28140545; s9427; ZINC56871302; AKOS015896776; CCG-267873; AC-26458; Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetrahydro-, methyl ester, (5-alpha,12-beta,19-alpha)-; CS-0016859; C09244; Q21099578
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  Formula C21H24N2O2
  Weight 336.4
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1
  InChI Key FNGGIPWAZSFKCN-ACRUOGEOSA-N
  Isomeric SMILES CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)CC=C2)C5=CC=CC=C5N3)C(=O)OC
  Canonical SMILES CCC12CC(=C3C4(C1N(CC4)CC=C2)C5=CC=CC=C5N3)C(=O)OC
  External Links PubChem ID 20485
CAS ID 4429-63-4
NPASS ID NPC123241
CHEMBL ID CHEMBL2011511
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Geomyces sp. strain CH1
  Factor Name: PDA medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy samples (stems and roots) of Nerium indicum were collected from Heng Mountain, Hunan province, China, and immediately packed and sent back to our laboratory within 24 h. The endophytic fungi initially were cultured on PDA plates at 27 ℃ for 3 days. Then, the endophytic fungi were inoculated in 250 mL Erlenmeyer flasks with 100 mL fermentation medium containing under a constant temperature incubator shaker (ZHWY-2102C; Shanghai Zhicheng Analytical Co., Ltd, China) in order to produce secondary metabolites. The fungi were grown at 27 ℃ at 170 rpm for 3 days and then incubated under still conditions for 4 days.
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               Factor Part Location NP Content
 
PDA medium (27℃ +7 days)
 Stems Hunan, China
NP Content: 0.102 µg/L
References
1 Indentification of vincamine indole alkaloids producing endophytic fungi isolated from Nerium indicum, Apocynaceae