Details of Natural Product (NP)

General Information of Natural Product (ID: NP1467)
  Natural Product Name
Salidroside
  Synonyms
Salidroside; 10338-51-9; Rhodioloside; Rhodosin; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol; UNII-M983H6N1S9; 2-(4-Hydroxyphenyl)ethyl beta-D-glucopyranoside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol; MFCD00210553; CHEBI:9009; CHEMBL465208; p-Hydroxyphenethyl glucopyranoside; M983H6N1S9; DSSTox_CID_28960; DSSTox_RID_83225; DSSTox_GSID_49034; CAS-10338-51-9; Glucopyranoside, p-hydroxyphenethyl; Tyrosol glucoside; Salidroside,(S); NCGC00169145-02; pyran-3,4,5-triol; salidroside (rhodioloside); Salidroside - Rhodioloside; beta-D-Glucopyranoside, 2-(4-hydroxyphenyl)ethyl; MLS006010734; SCHEMBL148079; 8-O-b-D-glucoside of tyrosol; MEGxp0_000478; Salidroside, analytical standard; DTXSID4049034; ACon1_000366; 2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol; HMS3884N15; AMY22501; HY-N0109; ZINC6092865; Tox21_113565; (4-hydroxyphenethoxy)tetrahydro-2H-; BDBM50269651; NSC741643; s2396; 4-hydroxyphenyl-2-ethylglucopyranoside; AKOS015895134; Tox21_113565_1; AC-6071; ACN-035412; CCG-267467; CM14012; CS-5300; MCULE-9369802025; NSC 741643; NSC-741643; Salidroside, >=95% (LC/MS-ELSD); NCGC00169145-01; NCGC00169145-03; SMR001294679; N1789; SW219124-1; 2-(4-Hydroxyphenyl)ethyl ?-D-glucopyranoside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-; C06046; 2-(4-Hydroxyphenyl)ethyl bet.-D-glucopyranoside; p-Hydroxyphenethyl alcohol 1-O-beta-D-glucoside; 338S519; A800725; Q-100031; Q7404463; BRD-K66030860-001-01-0; Salidroside, primary pharmaceutical reference standard; Salidroside, United States Pharmacopeia (USP) Reference Standard; (2R,3R,4S,5S,6R)-2-[2-(4-hydroxyphenyl)ethoxy]-6-methylol-tetrahydropyran-3,4,5-triol; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol
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  Formula C14H20O7
  Weight 300.3
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1
  InChI Key ILRCGYURZSFMEG-RKQHYHRCSA-N
  Isomeric SMILES C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O
  Canonical SMILES C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O
  External Links PubChem ID 159278
CAS ID 10338-51-9
NPASS ID NPC157338
HIT ID C0659
CHEMBL ID CHEMBL465208
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Lachnum sp. CJL-2014 strain Ra-R-12
  Factor Name: CD medium [1]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Mycelial extract)
 NA Changbai Mountain, China
NP Content: 0.131 ± 0.009 mg/mL
      Species Name: Leptosphaeria sp. CJL-2014 strain ZPRs-L-2
  Factor Name: CD medium [1]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Filtrate extract)
 NA Changbai Mountain, China
NP Content: 0.402 ± 0.248 mg/mL
      Species Name: Neonectria sp. CJL-2014 strain Rc-R-30
  Factor Name: CD medium [1]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Mycelial extract)
 NA Mila Pass, China
NP Content: 0.343 ± 0.465 mg/mL
      Species Name: Phialocephala sp. CJL-2014 strain Ra-S-13
  Factor Name: CD medium [1]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Filtrate extract)
 NA Changbai Mountain, China
NP Content: 1.729 ± 0.063 mg/mL
 
CD medium (Mycelial extract)
 NA Changbai Mountain, China
NP Content: 0.028 ± 0.032 mg/mL
 
CD medium (20℃ + 3 days + PH5 + Medium volume: 25ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.6264 ± 0.1482 mg/mL
 
CD medium (20℃ + 7 days + PH6 + Medium volume: 50ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.9082 ± 0.0720 mg/mL
 
CD medium (20℃ + 11 days + PH7 + Medium volume: 100ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.2076 ± 0.1359 mg/mL
 
CD medium (20℃ + 15 days + PH8 + Medium volume: 150ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.6904 ± 0.0822 mg/mL
 
CD medium (25℃ + 15 days + PH5 + Medium volume: 50ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.9383 ± 0.0475 mg/mL
 
CD medium (25℃ + 11 days + PH6 + Medium volume: 25ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 2.0502 ± 0.0477 mg/mL
 
CD medium (25℃ + 7 days + PH7 + Medium volume: 150ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 2.3392 ± 0.1093 mg/mL
 
CD medium (25℃ + 3 days + PH8 + Medium volume: 100ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.7475 ± 0.0789 mg/mL
 
CD medium (30℃ + 7 days + PH5 + Medium volume: 100ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.4483 ± 0.1551 mg/mL
 
CD medium (30℃ + 3 days + PH6 + Medium volume: 150ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.3964 ± 0.0129 mg/mL
 
CD medium (30℃ + 15 days + PH7 + Medium volume: 25ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.2126 ± 0.1286 mg/mL
 
CD medium (30℃ + 11 days + PH8 + Medium volume: 50ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.1450 ± 0.1473 mg/mL
 
CD medium (35℃ + 11 days + PH5 + Medium volume: 150ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.3489 ± 0.2708 mg/mL
 
CD medium (35℃ + 15 days + PH6 + Medium volume: 100ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.2687 ± 0.1773 mg/mL
 
CD medium (35℃ + 3 days + PH7 + Medium volume: 50ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.3894 ± 0.0478 mg/mL
 
CD medium (35℃ + 7 days + PH8 + Medium volume: 25ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.6011 ± 0.0927 mg/mL
References
1 Potential of the Endophytic Fungus Phialocephala fortinii Rac56 Found in Rhodiola Plants to Produce Salidroside and p-Tyrosol