Details of Natural Product (NP)

General Information of Natural Product (ID: NP1519)
  Natural Product Name
2-Hydroxy-1-(1H-Indol-3-Yl)Ethanone
  Synonyms
2-Hydroxy-1-(1H-indol-3-yl)ethanone; 2400-51-3; 3-Glyceroindole; 2-Hydroxy-1-(3-indolyl)ethanone; Ethanone, 2-hydroxy-1-(1H-indol-3-yl)-; Hydroxymethyl indol-3-yl ketone; INDOLE-3-KETOL; MFCD00466496; 2-hydroxy-1-(1H-indol-3-yl)-ethanone; 2-hydroxy-1-(1H-indol-3-yl)ethan-1-one; BRN 0142060; 3-(Hydroxyacetyl)-1H-indole; 3-hydroxyacetylindole; 3-(Hydroxyacetyl)Indole; Ethanone,2-hydroxy-1-(1H-indol-3-yl)-; 3-(hydroxyacetyl)-indole; ChemDiv3_003333; 3-(hydroxylacetyl)-indole; Cambridge id 5106709; Oprea1_735053; MLS001049127; CHEMBL524903; SCHEMBL4056357; DTXSID80178731; CHEBI:173472; HMS1482H11; ZINC192311; 2-hydroxy-1-(indol-3-yl)ethanone; CAA40051; AC5698; STK386423; AKOS005431093; Hydroxymethyl indol-3-yl ketone, 8CI; MCULE-4892238947; IDI1_021243; NCGC00182562-01; BS-36792; SMR000386954; SY131003; 2-Hydroxy-1-(1H-indol-3-yl)ethanone, 9CI
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  Formula C10H9NO2
  Weight 175.18
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C10H9NO2/c12-6-10(13)8-5-11-9-4-2-1-3-7(8)9/h1-5,11-12H,6H2
  InChI Key IBLZDDPFMAFWKP-UHFFFAOYSA-N
  Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C(=O)CO
  Canonical SMILES C1=CC=C2C(=C1)C(=CN2)C(=O)CO
  External Links PubChem ID 200631
CAS ID 2400-51-3
NPASS ID NPC154339
CHEMBL ID CHEMBL524903
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Aeromicrobium sp. strain LGMB491
  Factor Name: SG medium [1]
              Species Info Factor Info
               Experiment Detail
V. divergens leaves with no marks or injuries were collected from 21 plants located in the Pantanal sul-mato-grossense/Brazil, specifically in two regions of the Pantanal of Miranda, Abobral (19° 30′ 09.5″ S, 57° 02′ 32.2″ W) and Sao Bento (19° 28′ 53.9″ S, 57° 02′ 36.9″ W). A large-scale fermentation (10 L) of strain LGMB491 was performed using SG culture medium at 36 ℃ for 10 days.
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               Factor Part Location NP Content
 
SG medium (36℃ + 10 days)
 Leaves Pantanal, Brazil
NP Content: 1.5 mg
      Species Name: Jishengella endophytica 161111
  Factor Name: Fermentation medium [2]
              Species Info Factor Info
               Experiment Detail
Jishengella endophytica 161111 was isolated and identified from the healthy roots of the mangrove plant, Xylocarpus granatum, collected from the mangrove reserve zone in Hainan Province, China. The spores of J. endophytica 161111 were directly cultured in 1000 mL Erlenmeyer flasks containing 200 mL fermentation media consisted of glucose 2%, yeast extract 0.5%, peptone 0.5%, KNO3 1.5%, CaCO3 0.4%, and NaCl 0.4% (pH 7.2). The cultures were incubated on a rotatory shaker at 220 rpm at 28 ℃ for 30 days.
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               Factor Part Location NP Content
 
Fermentation medium containing glucose 2%, yeast extract 0.5%, peptone 0.5%, KNO3 1.5%, CaCO3 0.4%, and NaCl 0.4% (28℃ + 30 days + PH7.2 + 220 rpm)
 Roots Hainan Province, China
NP Content: 4 mg
References
1 Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil)
2 Alkaloids from the mangrove-derived actinomycete Jishengella endophytica 161111