Details of Natural Product (NP)

General Information of Natural Product (ID: NP1948)
  Natural Product Name
2-(4-Methylphenyl)Propan-2-Ol + Thymol
  Synonyms
2-(4-methylphenyl)propan-2-ol; 1197-01-9; p-Cymen-8-ol; 8-Hydroxy-p-cymene; 2-(p-tolyl)propan-2-ol; 2-(4-Methylphenyl)-2-propanol; 2-p-Tolyl-2-propanol; Dimethyl-p-tolyl carbinol; 1-Methyl-4-(1-hydroxy-1-methylethyl)benzene; 2-(P-Methylphenyl)-2-propanol; P-CYMENE-8-OL; UNII-6TFS69V5BW; para-Cymen-8-ol; p,alpha,alpha-Trimethylbenzyl alcohol; alpha,alpha,4-Trimethylbenzyl alcohol; p-Cymenol-8; alpha,alpha,4-Trimethylbenzenemethanol; Benzenemethanol, alpha,alpha,4-trimethyl-; 1-Methyl-4-(alpha-hydroxyisopropyl)benzene; 2-p-tolylpropan-2-ol; Benzenemethanol, .alpha.,.alpha.,4-trimethyl-; 6TFS69V5BW; Cymen-8-ol, p-; FEMA No. 3242; EINECS 214-817-7; NSC 361057; Trimethylbenzyl alcohol, P,alpha,alpha-; cherry propanol; AI3-00732; p-Cymenol; 8-p-cymenol; P-Cymen-alpha-ol; a-Hydroxy-p-cymene; Cimen-8-ol; Cymen-8-ol; NSC361057; p-Cymen-.alpha.-ol; 8-hydroxy para-cymene; Dimethyl-p-tolylcarbinol; DSSTox_CID_4890; p-(Hydroxyisopropyl)toluene; DSSTox_RID_77570; DSSTox_GSID_24890; laquo Rhoraquo -Cymene-8-ol; SCHEMBL858049; CHEMBL3186822; DTXSID0024890; p-Mentha-1,3,5-trien-8-ol; FEMA 3242; XLPDVYGDNRIQFV-UHFFFAOYSA-; CHEBI:167408; 2-(4-methylphenyl) propan-2-ol; Benzenemethanol, a,a,4-trimethyl-; ZINC1596590; Tox21_302135; a,a,4-Trimethylbenzenemethanol, 9CI; a,a,4-Trimethylbenzyl alcohol, 8CI; AKOS009996535; alpha,alpha,4-Trimethyl-Benzenemethanol; MCULE-6281738910; NSC-361057; 1,1-dimethyl-2-(4-methylphenyl)ethanol; NCGC00255334-01; AS-61419; CAS-1197-01-9; DB-012809; CS-0206670; FT-0652415; 1-Methyl-4-(.alpha.-hydroxyisopropyl)benzene; D86508; A804340; p,alpha,alpha-Trimethylbenzyl alcohol, >=95%, FG; Q27265496
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  Formula C10H14O
  Weight 150.22
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C10H14O/c1-8-4-6-9(7-5-8)10(2,3)11/h4-7,11H,1-3H3
  InChI Key XLPDVYGDNRIQFV-UHFFFAOYSA-N
  Isomeric SMILES CC1=CC=C(C=C1)C(C)(C)O
  Canonical SMILES CC1=CC=C(C=C1)C(C)(C)O
  External Links PubChem ID 14529
CAS ID 1197-01-9
NPASS ID NPC168855
CHEMBL ID CHEMBL3186822
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Tagetes patula
  Factor Name: Month Variation; Nitrogen Treatment; Phosphorus Treatment; Potassium Treatment [1]
              Species Info Factor Info
               Experiment Detail
The plants were cultivated in the Botanical Garden of the University of Agriculture, Plovdiv/Bulgaria on meadow-carbonate soil with neutral reaction (pH 7.1-7.2) and were harvested during the flowering period (July and September). The reserves of nitrogen, phosphorus and potassium in the soil (NPK) were: NH4+ 31.42 mg/kg; NO3- 16.66 mg/kg; P2O5 12.3 mg/100 g and K2O 11.4 mg/100 g. Ammonium nitrogen and nitrate nitrogen were extracted from the soil with a 1% solution of KCI and were determined by consecutive distillation on a Parnas-Vagner apparatus. Phosphorus was determined by the Egner-Ream method and potassium was extracted with 2 n HCI and was determined by flame photometry. The plants were grown as seedlings and were planted in a two-row bed 50 × (20 + 20) cm in patches of 5 m2. A scheme on the increase was used for the introduction of N, P and K fertilizers. The experiment was carried out as a randomized block modus - 15 variants in 4 replications (6 levels for N and 4 levels for P and K). Phosphorus (triple superphosphate - 50 % active substance) and potassium (potassium sulphate - 50 % active substance) were introduced only once before planting. Nitrogen (the ammonium nitrate - 33 % active substance) was introduced in three portions - during preparing of the soil, during the plants drafting (active vegetation) and at the full bloom.
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               Factor Function
The highest oil yield was obtained from leaves in July for N4P2K4 (0.63%) and the basic components were piperitenone (29.4%) and piperitone (13.5%). The mineral fertilization had no effect on the oil yield from the flowers. Regardless of the variant, it was found that the flower oils in July were rich in caryophyllene oxide (12.0-48.4%) and piperitenone (3.0-7.0%), while the oil composition in September was different.
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               Factor Part Location NP Content
 
Flower: (Harvesting time: July) + (Level of fertilization: N0P0K0)
 Flowers Plovdiv, Bulgaria
NP Content: 3 %
 
Flower: (Harvesting time: July) + (Level of fertilization: N2P4K4)
 Flowers Plovdiv, Bulgaria
NP Content: 0.9 %
 
Flower: (Harvesting time: July) + (Level of fertilization: N4P2K4)
 Flowers Plovdiv, Bulgaria
NP Content: 2.4 %
 
Flower: (Harvesting time: July) + (Level of fertilization: N4P4K2)
 Flowers Plovdiv, Bulgaria
NP Content: 2.5 %
 
Flower: (Harvesting time: September) + (Level of fertilization: N2P4K4)
 Flowers Plovdiv, Bulgaria
NP Content: 4 %
 
Flower: (Harvesting time: September) + (Level of fertilization: N4P2K4)
 Flowers Plovdiv, Bulgaria
NP Content: 1.7 %
 
Flower: (Harvesting time: September) + (Level of fertilization: N4P4K2)
 Flowers Plovdiv, Bulgaria
NP Content: 2.2 %
 
Leaf: (Harvesting time: July) + (Level of fertilization: N0P0K0)
 Leaves Plovdiv, Bulgaria
NP Content: 2.1 %
 
Leaf: (Harvesting time: July) + (Level of fertilization: N2P4K4)
 Leaves Plovdiv, Bulgaria
NP Content: 0.9 %
 
Leaf: (Harvesting time: July) + (Level of fertilization: N4P2K4)
 Leaves Plovdiv, Bulgaria
NP Content: 7.9 %
 
Leaf: (Harvesting time: July) + (Level of fertilization: N4P4K2)
 Leaves Plovdiv, Bulgaria
NP Content: 3.8 %
 
Leaf: (Harvesting time: September) + (Level of fertilization: N0P0K0)
 Leaves Plovdiv, Bulgaria
NP Content: 2 %
 
Leaf: (Harvesting time: September) + (Level of fertilization: N2P4K4)
 Leaves Plovdiv, Bulgaria
NP Content: 1 %
 
Leaf: (Harvesting time: September) + (Level of fertilization: N4P2K4)
 Leaves Plovdiv, Bulgaria
NP Content: 1.1 %
 
Leaf: (Harvesting time: September) + (Level of fertilization: N4P4K2)
 Leaves Plovdiv, Bulgaria
NP Content: 1.9 %
References
1 Effect of Mineral Fertilization on the Essential Oil Composition of Tagetes patula L. from Bulgaria