General Information of Natural Product (ID: NP1995)
  Natural Product Name
3-Methyl-4,8-dihydroxy-3,4-dihydroisocoumarin
  Synonyms
33788-22-6|4-hydroxymellein|4,8-dihydroxy-3-methyl-isochroman-1-one|4,8-dihydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one|(-)-trans-3,4-Dihydro-4,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one|Isocoumarin, 3,4-dihydro-4,8-dihydroxy-3-methyl-|4-Hydroxychracin|3-Methyl-4,8-dihydroxy-3,4-dihydroisocoumarin|1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-|SCHEMBL7606551|CHEMBL3985330|DTXSID80955367|CHEBI:141335|BS-1290
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  Formula C10H10O4
  Weight 194.18
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C10H10O4/c1-5-9(12)6-3-2-4-7(11)8(6)10(13)14-5/h2-5,9,11-12H,1H3
  InChI Key STSOHAOGZMLWFR-UHFFFAOYSA-N
  Isomeric SMILES CC1C(C2=C(C(=CC=C2)O)C(=O)O1)O
  Canonical SMILES CC1C(C2=C(C(=CC=C2)O)C(=O)O1)O
  External Links PubChem ID 169539
CAS ID 33788-22-6
CHEMBL ID CHEMBL3985330
  NP Activity Charts   Click to show/hide

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Hyalodendriella sp. Ponipodef 12
  Factor Name: PDB Medium [1]
              Species Info Factor Info
               Experiment Detail
The fungus was obtained from the fresh leaves of Euphorbia sieboldiana, which were collected from the campus of China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China, in April 2013. After cultivation on potato dextrose agar (PDA) at 28 °C for 7 days, two pieces of the agar (about 1.0 cm3) were added to an Erlenmeyer flask (500 mL) with 150 mL of potato dextrose liquid medium, and the flask was incubated on a rotary shaker at 28 °C and 150 rpm for 5 days to prepare seed culture. Solid fermentation was carried out in 12 Erlenmeyer flasks (500 mL) each containing 120 g of sterilized rice and 10 mL of seed culture, and the flaks were cultivated at 28 °C for 30 days.
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               Factor Part Location NP Content
 
PDB Medium (25 degrees Celsius + 20Days + 150 rpm)
healthy stems China
NP Content: 12 mg
References
1 Benzopyranones from the endophytic fungus Hyalodendriella sp. Ponipodef12 and their bioactivities