Details of Natural Product (NP)

General Information of Natural Product (ID: NP2022)
  Natural Product Name
cytochalasin D
  Synonyms
cytochalasin D|22144-77-0|Zygosporin A|UNII-SY9F0FZ3TO|Cytohalasin D|Lygosporin A|SY9F0FZ3TO|MFCD00077706|NSC209835|C30H37NO6|HSDB 3549|3eks|EINECS 244-804-1|NSC 209835|SCHEMBL33529|(11)Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)-|CHEMBL260287|HY-N6682|AKOS030213128|ZINC100058047|1H-Cycloundec(d)isoindole-1,11(2H)-dione, 3-benzyl-3,3-alpha4,5,6,6-alpha,9,10,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-, 15-acetate|Cytochalasin D, from Zygosporium mansonii|CS-0012977|W1020|Q5201339|(benzyl-dihydroxy-trimethyl-methylene-dioxo-[?]yl) acetate|Cytochalasin D, from Zygosporium mansonii, >=98% (TLC and HPLC), powder|(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,151R)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate|1H-Cycloundec(d)isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-|1H-Cycloundec(d)isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*))-|1H-Cycloundec(d)isoindole-1,11(2H)-dione, 3-benzyl-3,3-alpha,4,5,6,6-alpha,9,10,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-, 15-acetate|1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6-12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-|7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl(11)cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate|Cytochalasin D, Ready Made Solution, from Zygosporium mansonii, 5 mg/mL in DMSO, 0.2 mum filtered
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  Formula C30H37NO6
  Weight 507.6
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
  InChI Key SDZRWUKZFQQKKV-JHADDHBZSA-N
  Isomeric SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O
  Canonical SMILES CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O
  External Links PubChem ID 5458428
CAS ID 22144-77-0
NPASS ID NPC239770
CHEMBL ID CHEMBL260287
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Xylaria sp. G12
  Factor Name: PDB Medium [1]
              Species Info Factor Info
               Experiment Detail
The endophytic fungus Coniothyrium sp., internal strain No. zw86, was isolated from the plant Salsola oppostifolia, growing on Gomera, in the Canary Islands. It was cultivated on 12 l of 5% w/v biomalt solid agar medium at room temperature for 28 days.
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               Factor Part Location NP Content
 
PDB Medium (25 degrees Celsius + 21Days)
 branch Songkhla province, Thailand
NP Content: 33.3 mg
References
1 Indanone and mellein derivatives from the Garcinia-derived fungus Xylaria sp. PSU-G12