Details of Natural Product (NP)

General Information of Natural Product (ID: NP2031)
  Natural Product Name
Myriocin
  Synonyms
Myriocin|thermozymocidin|35891-70-4|ISP-I|ISP-1|Myriocin from Mycelia sterilia|UNII-YRM4E8R9ST|(2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid|CHEBI:582124|YRM4E8R9ST|(E,2S,3R,4R)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid|(2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid|NCGC00163597-02|NCGC00163597-03|DSSTox_CID_26360|DSSTox_RID_81561|DSSTox_GSID_46360|CAS-35891-70-4|SR-05000002333|C21H39NO6|antibiotic ISP-I|VRP|Myriocin; ISP-1|Myriocin,mycella sterilia|CHEMBL55076|GTPL6664|SCHEMBL6542261|SCHEMBL8499386|DTXSID9046360|(E,2R,3S,4S)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid|HMS3649I03|HY-N6798|ZINC5782527|Tox21_112062|Tox21_113400|1865AH|BDBM50461646|LMFA01060203|MFCD01632772|Tox21_112062_1|CCG-208239|CS-W020835|NCGC00163597-01|NCGC00163597-04|6-Eicosenoic acid, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-, (2S-(2R*,3S*,4S*,6E))-|C19914|Myriocin, Mycelia sterilia - CAS 35891-70-4|Q6948247|SR-05000002333-2|SR-05000002333-3|Myriocin from Mycelia sterilia, >=98% (HPLC), powder|(2S,3R,4R,E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
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  Formula C21H39NO6
  Weight 401.5
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1
  InChI Key ZZIKIHCNFWXKDY-GNTQXERDSA-N
  Isomeric SMILES CCCCCCC(=O)CCCCCC/C=C/C[C@H]([C@@H]([C@@](CO)(C(=O)O)N)O)O
  Canonical SMILES CCCCCCC(=O)CCCCCCC=CCC(C(C(CO)(C(=O)O)N)O)O
  External Links PubChem ID 6438394
CAS ID 35891-70-4
NPASS ID NPC258824
CHEMBL ID CHEMBL55076
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Mycosphaerella sp. UFMGCB 2032
  Factor Name: PDA Medium [1]
              Species Info Factor Info
               Experiment Detail
A. terreus was isolated from the internal tissue of the healthy roots of Carthamus lanatus L. (Asteraceae), which collected from the wildly growing plant at Al-Azhar University campus in February 2013. Mass growth of the fungus for the isolation and identification of its metabolites was carried out in 1 L Erlenmeyer flasks (each flask containing 100 mL of distilled water were added to 100 g commercially available rice and kept overnight prior to autoclaving). The fungus was grown on rice solid medium (8 flasks) at room temperature under septic conditions for 4 weeks.
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               Factor Part Location NP Content
 
PDA Medium (25 ± 2 degrees Celsius + 15Days)
 Leaves Savannah, Brazil
NP Content: 21.5 mg
References
1 Endophytic fungal compounds active against Cryptococcus neoformans and C. gattii