Details of Natural Product (NP)

General Information of Natural Product (ID: NP1279)
  Natural Product Name
Diaporthin
  Synonyms
Diaporthin; UNII-348G93MX9Z; 10532-39-5; 348G93MX9Z; CHEMBL4163739; DTXSID60909444; 8-hydroxy-3-[(2S)-2-hydroxypropyl]-6-methoxyisochromen-1-one; Isocoumarin, 8-hydroxy-3-(2-hydroxypropyl)-6-methoxy-, (+)-; (S)-8-Hydroxy-3-(2-hydroxypropyl)-6-methoxy-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one, 8-hydroxy-3-(2-hydroxypropyl)-6-methoxy-, (S)-; MCULE-1550359073; Q27256349; 8-Hydroxy-3-(2-hydroxypropyl)-6-methoxy-1H-2-benzopyran-1-one; NCGC00384779-01!8-hydroxy-3-[(2S)-2-hydroxypropyl]-6-methoxyisochromen-1-one; 6512-79-4
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  Formula C13H14O5
  Weight 250.25
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C13H14O5/c1-7(14)3-10-5-8-4-9(17-2)6-11(15)12(8)13(16)18-10/h4-7,14-15H,3H2,1-2H3/t7-/m0/s1
  InChI Key ORLHWDAVUBPRKN-ZETCQYMHSA-N
  Isomeric SMILES C[C@@H](CC1=CC2=CC(=CC(=C2C(=O)O1)O)OC)O
  Canonical SMILES CC(CC1=CC2=CC(=CC(=C2C(=O)O1)O)OC)O
  External Links PubChem ID 5323561
CAS ID 10532-39-5
CHEMBL ID CHEMBL4163739
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Diaporthe terebinthifolii LGMF907
  Factor Name: MEB medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal culture: The strain D. terebinthifolii LGMF907 was obtained from leaves of S. terebinthifolius Raddi collected in Curitiba, Parana, Brazil (25° 28′ 31.847″ S, 49° 17′ 5.629″ W). Strain LGMF907 was grown on potato dextrose agar (PDA; IBI Scientific) plates at 28 ℃ for 15-20 days. Large-scale fermentation: The large-scale cultivation was performed by inoculation of 24 agar plugs into 2-L Erlenmeyer flasks containing 800 mL of malt extract broth (MEB; 20 g/L malt extract, 20 g/L glucose, and 1 g/L peptone), with a total of 20 L of culture. The flasks were incubated for 10 days, at pH 5.8, 28 ℃, and 120 rpm.
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               Factor Part Location NP Content
 
MEB medium (28℃ + 10 days + PH5.8)
 NA Curitiba, Parana, Brazil
NP Content: 2 mg
References
1 Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds