Details of Natural Product (NP)

General Information of Natural Product (ID: NP1318)
  Natural Product Name
4-Hydroxy-1-Methyl-2-Quinolone
  Synonyms
4-Hydroxy-1-methyl-2-quinolone; 1677-46-9; 4-Hydroxy-1-methyl-2(1H)-quinolone; 4-hydroxy-1-methylquinolin-2(1H)-one; 4-Hydroxy-1-methylcarbostyril; 2(1H)-Quinolinone, 4-hydroxy-1-methyl-; 1-Methyl-4-hydroxycarbostyril; 4-Hydroxy-N-methylcarbostyril; 1-Methyl-4-hydroxy-2-chinolon; 4-Hydroxy-1-methyl-2(1H)-quinolinone; CARBOSTYRIL, 4-HYDROXY-1-METHYL-; N-Methyl-4-hydroxykarbostyril; 1-Methyl-4-hydroxy-2-chinolinon; 4-hydroxy-1-methylquinolin-2-one; NSC 39973; NSC39973; N-Methyl-4-hydroxykarbostyril [Czech]; 1-Methyl-4-hydroxy-2-chinolon [Czech]; UNII-V713CAW761; V713CAW761; MFCD00024052; 4-HYDROXY-1-METHYL-1H-2-QUINOLINONE; N-Methyl-4-hydroxykarbostyril (CZECH); 1-Methyl-4-hydroxy-2-chinolon (CZECH); 4-hydroxy-1-methyl-1,2-dihydroquinolin-2-one; EINECS 216-830-3; 4-Hydroxy-1-methyl-1H-quinolin-2-one; BRN 1528990; 1-Methyl-4-hydroxy-2-chinolinon [Czech]; 2(1H)-Quinolinone,4-hydroxy-1-methyl-; Maybridge1_002182; Oprea1_834130; 5-21-12-00311 (Beilstein Handbook Reference); SCHEMBL835056; 4-Hydroxy-1-methyl carbostyril; CHEMBL2022051; DTXSID0061874; SCHEMBL13143143; HMS547L04; WLN: T66 BNVJ B1 EQ; n-methyl-4-hydroxy-2-quinolinone; 4-hydroxy-1-methyl-quinolin-2-one; ALBB-019832; BBL036914; NSC-39973; STK327478; STL514059; ZINC18190627; AKOS000121455; AKOS037491726; ZINC103644054; MCULE-8793371318; SDCCGMLS-0065887.P001; 1-methyl-4-hydroxy-2(1H)-quinolinone; 1-methyl-4-hydroxyquinolin-2(1H)-one; 2-hydroxy-1-methylquinolin-4(1H)-one; UPCMLD0ENAT5889157:001; NS-01441; AB0076524; DB-043712; EU-0087440; FT-0618613; M1009; 4-Hydroxy-1-methyl-2(1H)-quinolone, 98%; AB00694265-02; A810900; W-109693
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  Formula C10H9NO2
  Weight 175.18
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C10H9NO2/c1-11-8-5-3-2-4-7(8)9(12)6-10(11)13/h2-6,12H,1H3
  InChI Key RTNPPPQVXREFKX-UHFFFAOYSA-N
  Isomeric SMILES CN1C2=CC=CC=C2C(=CC1=O)O
  Canonical SMILES CN1C2=CC=CC=C2C(=CC1=O)O
  External Links PubChem ID 54686436
CAS ID 1677-46-9
CHEMBL ID CHEMBL2022051
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Penicillium citrinum strain TPDTF1.4
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal material: The fungus P. citrinum (strain no. TPDTF1.4) was isolated under sterile conditions from the flowers of O. tenuiflorum (Lamiaceae) collected in Denpasar, Bali, Indonesia in 2011. The fungal strain was cultivated on rice or white beans, which were prepared by autoclaving 100 g rice or beans and 100 mL water in a 1 L Erlenmeyer flask. Fermentation was performed on rice medium in one flask for 27 days at room temperature under static conditions. Meanwhile a static cultivation was conducted on beans medium in two flasks for 17 days at room temperature.
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               Factor Part Location NP Content
 
Rice medium (25℃ + 27 days)
 Flowers Denpasar, Bali, Indonesia
NP Content: 1.2 mg
References
1 Bioactive polyketides and alkaloids from Penicillium citrinum, a fungal endophyte isolated from Ocimum tenuiflorum