Details of Natural Product (NP)

General Information of Natural Product (ID: NP1321)
  Natural Product Name
Citrinin
  Synonyms
citrinin; 518-75-2; (-)-citrinin; Citriain; (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; UNII-3S697X6SNZ; NSC186; 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-; 3S697X6SNZ; CHEBI:48707; MFCD00006912; (3R,4S)-6-hydroxy-3,4,5-trimethyl-8-oxo-3,4-dihydroisochromene-7-carboxylic acid; (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid; (3R-trans)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-3,4-dihydroisochromene-7-carboxylic acid; CCRIS 175; HSDB 3473; EINECS 208-257-2; BRN 0088597; NSC-186; 3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxobenzo(c)pyran-7-carboxylic acid; Citrinin, 98%; Spectrum_000451; Spectrum2_000734; Spectrum3_000240; Spectrum4_001804; Spectrum5_000507; BSPBio_001919; KBioGR_002411; KBioSS_000931; SPECTRUM210186; 5-18-09-00061 (Beilstein Handbook Reference); DivK1c_000646; SCHEMBL157775; SPBio_000688; DTXSID8020333; HMS502A08; KBio1_000646; KBio2_000931; KBio2_003499; KBio2_006067; KBio3_001419; NINDS_000646; HMS1923C05; CCG-39048; ZINC19795941; AKOS030254668; SDCCGMLS-0066537.P001; Citrinin 100 microg/mL in Acetonitrile; IDI1_000646; NCGC00160164-01; NCGC00160164-02; NCGC00160164-03; NCI60_001544; Q420354; SR-05000002496; WLN: T66 CO HV AUT&J D1 E1 G1 IVQ JQ; SR-05000002496-1; Citrinin, from Penicillium citrinum, >=98% (HPLC); Q63392265; Citrinin solution, 100 mug/mL in acetonitrile, analytical standard; (3R,4S)-3,4,5-Trimethyl-6-hydroxy-8-oxo-4,8-dihydro-3H-2-benzopyran-7-carboxylic acid; 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-; 8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid #; 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-,(3R,4S)-; 3H-2-Benzopyran-7-carboxylic acid,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-; 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo, (3R-trans)-3H-2-benzopyran-7-carboxylic acid
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  Formula C13H14O5
  Weight 250.25
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,14H,1-3H3,(H,16,17)/t5-,7-/m1/s1
  InChI Key CBGDIJWINPWWJW-IYSWYEEDSA-N
  Isomeric SMILES C[C@@H]1[C@H](OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C
  Canonical SMILES CC1C(OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C
  External Links PubChem ID 54680783
CAS ID 518-75-2
CHEMBL ID CHEMBL510139
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Penicillium citrinum strain TPDTF1.4
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal material: The fungus P. citrinum (strain no. TPDTF1.4) was isolated under sterile conditions from the flowers of O. tenuiflorum (Lamiaceae) collected in Denpasar, Bali, Indonesia in 2011. The fungal strain was cultivated on rice or white beans, which were prepared by autoclaving 100 g rice or beans and 100 mL water in a 1 L Erlenmeyer flask. Fermentation was performed on rice medium in one flask for 27 days at room temperature under static conditions. Meanwhile a static cultivation was conducted on beans medium in two flasks for 17 days at room temperature.
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               Factor Part Location NP Content
 
Rice medium (25℃ + 27 days)
 Flowers Denpasar, Bali, Indonesia
NP Content: 11.5 mg
References
1 Bioactive polyketides and alkaloids from Penicillium citrinum, a fungal endophyte isolated from Ocimum tenuiflorum