Isolation of fungal material: The three-year-old healthy P. notoginseng was collected from Wenshan, Yunnan province of China. After surface sterilization with 75% EtOH for 60 s, the root of P. notoginseng was rinsed in sterile water. Fermentation: Fermentation was carried out in 50 Erlenmeyer flasks (250 mL) each containing 75 g rice. Sterile water (100 mL) was added to each flask, and the contents were autoclaved at 121 ℃ for 30 min. After cooling to room temperature, each flask was inoculated with 2.0 mL of the spore and incubated at 28 ℃ for 30 days.