Details of Natural Product (NP)

General Information of Natural Product (ID: NP1378)
  Natural Product Name
Kojic Acid
  Synonyms
kojic acid; 501-30-4; 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one; 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-; 5-Hydroxy-2-(hydroxymethyl)-4-pyrone; 5-hydroxy-2-(hydroxymethyl)pyran-4-one; 5-Hydroxy-2-hydroxymethyl-4-pyrone; acido kojico; 2-Hydroxymethyl-5-hydroxy-gamma-pyrone; 2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one; MFCD00006580; UNII-6K23F1TT52; 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone; 5-Hydroxy-2-hydroxymethyl-pyran-4-one; 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one; Pyran-4-one, 5-hydroxy-2-(hydroxymethyl); CHEMBL287556; CHEBI:43572; NSC1942; 6K23F1TT52; NCGC00017325-03; NCGC00017325-06; DSSTox_CID_20236; DSSTox_RID_79455; DSSTox_GSID_40236; 123712-78-7; CAS-501-30-4; CCRIS 4131; NSC 1942; EINECS 207-922-4; BRN 0120895; Kojisaeure; AI3-02549; HSDB 7664; Kojic Acid Solution; Spectrum_000191; Spectrum2_001828; Spectrum3_001704; Spectrum4_000571; Spectrum5_001085; Natural Kojic Acid Powder; Kojic Acid Dipalmitate 5kg; Oprea1_038773; SCHEMBL36895; BSPBio_003288; KBioGR_001002; KBioSS_000671; 5-18-02-00516 (Beilstein Handbook Reference); BIDD:ER0501; DivK1c_000923; SPBio_001875; Kojic acid, analytical standard; MEGxm0_000388; WLN: T6O DVJ B1Q EQ; DTXSID2040236; ACon1_000622; BEJNERDRQOWKJM-UHFFFAOYSA-; HMS502O05; KBio1_000923; KBio2_000671; KBio2_003239; KBio2_005807; KBio3_002508; NINDS_000923; HMS3604L04; KUC106760N; NSC-1942; TNP00261; 2-Hydroxymethyl-5-hydroxy-?-pyrone; 2-Hydroxymethyl-5-Hydroxy-G-Pyrone; Tox21_110814; Tox21_113449; BBL010645; BDBM50031467; CCG-38458; s5174; STK801688; ZINC13831818; AKOS000120649; Tox21_110814_1; 5-Hydroxy-2-hydroxymethyl-I(3)-pyron; DB01759; HY-W050154; MCULE-1079267668; IDI1_000923; SMP1_000171; NCGC00017325-01; NCGC00017325-02; NCGC00017325-04; NCGC00017325-05; NCGC00017325-10; NCGC00142361-01; NCGC00168903-01; NCGC00168903-02; NCGC00181145-01; AC-11658; AS-11648; H802; Kojic acid, purum, >=98.0% (HPLC); KSC-11-228-2; SY018009; 2-HYDROXYMETHYL-5-HYDROXY-4-PYRONE; 2-Hydroxymethyl-5-hydroxy-4H-pyran-4-one; CS-0032701; FT-0627581; K0010; K0012; 01K304; C91105; K-7000; Q416285; SR-01000945134; SR-01000945134-1; 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one Solution; C65A72E0-0E46-4AF4-AA68-178ECA2E5FCC; F0001-1307; Z381040328
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  Formula C6H6O4
  Weight 142.11
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
  InChI Key BEJNERDRQOWKJM-UHFFFAOYSA-N
  Isomeric SMILES C1=C(OC=C(C1=O)O)CO
  Canonical SMILES C1=C(OC=C(C1=O)O)CO
  External Links PubChem ID 3840
CAS ID 501-30-4
NPASS ID NPC116366
HIT ID C0168
CHEMBL ID CHEMBL287556
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Aspergillus flocculosus strain CBS 112784
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal material: The endophytic fungus was isolated from the fresh stems of Markhamia platycalyx family (Bignoniaceae) collected in October 2010 from Al-Zohriya gardens (Al-Zamalek, Giza, Egypt). Small-scale fermentation: A small-scale fermentation was carried out in two Erlenmeyer flasks (1 L each) on rice medium, which was prepared with 100 g of rice powder and approximately 100 mL of demineralized water just enough to cover the rice layer. The rice media was autoclaved prior to fungal inoculation. A 15-day fungal inoculum grown on petri dish was inoculated on the sterile rice medium and was allowed to grow at room temperature under static condition for 30 days. Medium-scale 30-day rice culture fermentation: A medium scale fermentation was performed in 10 Erlenmeyer flasks (1 L each) on rice solid medium for 30 days under same condition applied to small scale culture.
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               Factor Part Location NP Content
 
Medium-scale fermentation: Rice medium (25℃ + 30 days)
 Fresh stems Al-Zamalek, Giza, Egypt
NP Content: 4.8 mg
References
1 Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics