Details of Natural Product (NP)

General Information of Natural Product (ID: NP1394)
  Natural Product Name
4-Hydroxyphenylacetic Acid
  Synonyms
4-hydroxyphenylacetic acid; 156-38-7; 2-(4-hydroxyphenyl)acetic acid; p-hydroxyphenylacetic acid; (4-Hydroxyphenyl)acetic acid; benzeneacetic acid, 4-hydroxy-; 4-Hydroxybenzeneacetic acid; 4-hydroxyphenylacetate; (p-Hydroxyphenyl)acetic acid; Parahydroxy phenylacetic acid; 4-Carboxymethylphenol; Acetic acid, (p-hydroxyphenyl)-; 4-Hydroxyphenyl acetic acid; MFCD00004347; UNII-3J9SHG0RCN; p-hydroxyphenylacetate; Parahydroxy phenylacetate; 3J9SHG0RCN; p-Hydroxyphenyl acetic acid; 4-hydroxyphenyl-acetic acid; CHEMBL1772; 4-hydroxy phenyl acetic acid; (4-hydroxy-phenyl)-acetic acid; CHEBI:18101; 4-hydroxybenzeneacetate; 4HP; (p-hydroxyphenyl)acetate; 4-HPA; EINECS 205-851-3; NSC 25066; BRN 1448766; AI3-17755; 3pcg; Parahydroxyphenylacetate; 1ai6; 4-Hydroxy-Benzeneacetate; 4-hydroxyphenyacetic acid; 4-hydroxyphenylactic acid; 4-hyroxyphenylacetic acid; (p-hydroxyphenyl)-Acetate; ChemDiv3_005483; bmse000455; 4- hydroxyphenylacetic acid; 4-hydroxy-phenylacetic acid; 4-hydroxyphenylethanoic acid; (4-hydroxy-phenyl)-acetate; p-hydroxy phenyl acetic acid; 4-Hydroxy-Benzeneacetic acid; 4-Hydroxybenzene acetic acid; SCHEMBL75700; 4-hydroxy-phenyl acetic acid; 4-10-00-00543 (Beilstein Handbook Reference); MLS001066398; (p-hydroxyphenyl)-Acetic acid; (4-hydroxyphenyl) acetic acid; (4-hydroxyphenyl)-acetic acid; (4-hydroxyphenyl)ethanoic acid; Acetic acid, 4-hydroxyphenyl-; (4-Hydroxy-phenyl)-essigsaeure; 4-Hydroxyphenylacetic Acid,(S); DTXSID5059745; 4-Hydroxyphenylacetic acid, 98%; HMS1488J05; HMS2760I07; ZINC213065; 2-[4-(hydroxy)phenyl)acetic acid; CS-D1503; HY-N1902; NSC25066; NSC27460; AC7824; BBL027456; BDBM50339586; NSC-25066; NSC-27460; s4863; STL377918; AKOS000277614; AM84511; CCG-266227; LS10592; MCULE-7254180433; PS-5568; IDI1_023393; AC-10104; SMR000020068; SY004128; DB-043314; EU-0016214; FT-0618732; H0290; EN300-18714; C00642; H-7100; A809742; AM-814/41090691; Q4637160; 4-Hydroxyphenylacetic acid, Vetec(TM) reagent grade, 98%; B977C251-72C6-4D13-AD85-937DCA3E6AF2
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  Formula C8H8O3
  Weight 152.15
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
  InChI Key XQXPVVBIMDBYFF-UHFFFAOYSA-N
  Isomeric SMILES C1=CC(=CC=C1CC(=O)O)O
  Canonical SMILES C1=CC(=CC=C1CC(=O)O)O
  External Links PubChem ID 127
CAS ID 156-38-7
NPASS ID NPC52472
CHEMBL ID CHEMBL1772
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Aspergillus flocculosus strain CBS 112784
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal material: The endophytic fungus was isolated from the fresh stems of Markhamia platycalyx family (Bignoniaceae) collected in October 2010 from Al-Zohriya gardens (Al-Zamalek, Giza, Egypt). Small-scale fermentation: A small-scale fermentation was carried out in two Erlenmeyer flasks (1 L each) on rice medium, which was prepared with 100 g of rice powder and approximately 100 mL of demineralized water just enough to cover the rice layer. The rice media was autoclaved prior to fungal inoculation. A 15-day fungal inoculum grown on petri dish was inoculated on the sterile rice medium and was allowed to grow at room temperature under static condition for 30 days. Medium-scale 30-day rice culture fermentation: A medium scale fermentation was performed in 10 Erlenmeyer flasks (1 L each) on rice solid medium for 30 days under same condition applied to small scale culture.
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               Factor Part Location NP Content
 
Medium-scale fermentation: Rice medium (25℃ + 30 days)
 Fresh stems Al-Zamalek, Giza, Egypt
NP Content: 15 mg
      Species Name: Colletotrichum gloeosporioides Mc-7
  Factor Name: PDB Medium [2]
              Species Info Factor Info
               Experiment Detail
Authenticated M. champaca was collected in the Chemistry Institute, Sao Paulo State University (UNESP), Araraquara, Sao Paulo, Brazil, in April of 2004. Endophytic fungi were isolated from the leaves, stems and roots of healthy, adult M. champaca, which was subjected to surface sterilization. C. gloeosporioides was cultured on a larger scale and inoculated into six Erlenmeyer flasks (4 L), each containing PDB medium (3.0 L), and incubated at 25 °C on rotary shakers at 150 rpm for 28 days.
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               Factor Part Location NP Content
 
PDB Medium (25 degrees Celsius + 28Days + 150 rpm)
 leaves, stems and roots Sao Paulo State University (UNESP), Araraquara, Sao Paulo, Brazil
NP Content: 20.5 mg
References
1 Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics
2 Antifungal compounds produced by Colletotrichum gloeosporioides, an endophytic fungus from Michelia champaca