Details of Natural Product (NP)

General Information of Natural Product (ID: NP1468)
  Natural Product Name
2-(4-Hydroxyphenyl)Ethanol
  Synonyms
Tyrosol; 2-(4-Hydroxyphenyl)ethanol; 501-94-0; 4-Hydroxyphenethyl alcohol; 4-(2-Hydroxyethyl)phenol; 4-Hydroxyphenylethanol; p-Hydroxyphenethyl alcohol; 4-Hydroxybenzeneethanol; Benzeneethanol, 4-hydroxy-; p-Tyrosol; p-hydroxyphenylethanol; 4-Hydroxyphenylethyl alcohol; 2-(4-Hydroxyphenyl)ethyl Alcohol; p-Thyrosol; UNII-1AK4MU3SNX; MFCD00002902; NSC 59876; p-HPEA; 2-(P-HYDROXYPHENYL)ETHANOL; Metoprolol IMpurity 07; 4-hydroxy-Benzeneethanol; 1AK4MU3SNX; p-Hydroxyphenylethyl alcohol; 4-(2-Hydroxy-ethyl)-phenol; CHEMBL53566; CHEBI:1879; 2-(4-Hydroxyphenyl)ethanol (Tyrosol); Tyrosol C; SMR000857159; 4-hydroxyphenethylalcohol; EINECS 207-930-8; beta-(4-Hydroxyphenyl)ethanol; 4-tyrosol; 2-(4-Hydroxyphenyl)ethan-1-ol; YRL; PHEP; Tyrosol ,(S); 4-hydroxybenzenethanol; 4-(Hydroxyethyl)phenol; p-Hydroxy-benzeneethanol; b-(p-Hydroxyphenyl)ethanol; bmse000173; b-(4-Hydroxyphenyl)ethanol; 4-Hydroxyphenylmethylcarbinol; 2-(p-hydroxyphenyl) ethanol; SCHEMBL43838; (4-Hydroxyphenethyl) alcohol; 2-(4-hydroxyphenyl) ethanol; 2-(4-hydroxyphenyl)-ethanol; beta-(p-Hydroxyphenyl)ethanol; MLS001332423; MLS001332424; Phenethyl alcohol, p-hydroxy-; Ethanol, 2-(4-hydroxyphenyl); DTXSID8060111; SCHEMBL10620528; .beta.-(p-Hydroxyphenyl)ethanol; 2-(4-Hydroxyphenyl)-1-ethanol; Ethanol, 2-(4-hydroxyphenyl)-; .beta.-(4-Hydroxyphenyl)ethanol; OTAVA-BB 1204410; AKOS 91052; HMS2230E12; ZINC164581; 2-(4-Hydroxyphenyl)ethanol, 98%; BCP34277; HY-N0474; NSC59876; STR02735; BDBM50339585; NSC-59876; s3773; AKOS000280287; AC-2493; AS00553; CCG-266147; CM10966; CS-W019782; KS-5274; MCULE-9268661621; NCGC00246994-01; SY001653; DB-019455; AM20060146; FT-0608647; H0720; N1496; A14486; C06044; 2-(4-Hydroxyphenyl)ethanol, analytical standard; NSC 59876; p-HPEA;4-Hydroxyphenethyl alcohol; Q402607; F0001-1309; 947D0361-23C6-4863-8346-22AB05108AC5; 4-hydroxy-Benzeneethanol;4-Hydroxyphenylethanol;beta-(4-Hydroxyphenyl)ethanol
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  Formula C8H10O2
  Weight 138.16
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H2
  InChI Key YCCILVSKPBXVIP-UHFFFAOYSA-N
  Isomeric SMILES C1=CC(=CC=C1CCO)O
  Canonical SMILES C1=CC(=CC=C1CCO)O
  External Links PubChem ID 10393
CAS ID 501-94-0
NPASS ID NPC300017
HIT ID C0467
CHEMBL ID CHEMBL53566
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Fusarium chlamydosporium
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
In March 2013, Anvillea garcinii (Burm.f.) DC. (Asteraceae) was obtained from the wildly growing plant at Al-Azhar University campus. A sample from preserved fungus (FuC/March 2013) was cultivated on solid rice cultures (10 Erlenmeyer flasks × 1L). The cultures were incubated at room temperature under a septic condition for 30 days.
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               Factor Part Location NP Content
 
Solid rice medium (25℃ + 30 days)
 Leaves inner tissues Al-Azhar University, Cairo, Egypt
NP Content: 5.6 mg
      Species Name: Lachnum sp. CJL-2014 strain Ra-R-12
  Factor Name: CD medium [2]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Mycelial extract)
 NA Changbai Mountain, China
NP Content: 0.113 ± 0.010 mg/mL
      Species Name: Leptosphaeria sp. CJL-2014 strain ZPRs-L-2
  Factor Name: CD medium [2]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Filtrate extract)
 NA Changbai Mountain, China
NP Content: 0.083 ± 0.117 mg/mL
      Species Name: Neonectria sp. CJL-2014 strain Rc-R-30
  Factor Name: CD medium [2]
      Species Name: Phialocephala sp. CJL-2014 strain Ra-S-13
  Factor Name: CD medium [2]
              Species Info Factor Info
               Experiment Detail
R. crenulata samples were collected from Mila Pass (altitude 5007 m, E 92° 22′ 31″ -92° 24′ 88″ , N 29° 44′ 33″ -29° 46′ 56″), and R. sachalinensis and R. angusta were collected from Changbai Mountain (altitude 2200 m, E 128° 08′ 17″ -128° 11′ 10″ , N 44° 11′ 20″ -44° 13′ 29″) of China. Six pieces (5 mm diameter) of mycelial agar plugs from the edge of growing cultures of endophytic fungi were each inoculated into 500 mL Erlenmeyer flask with 200 mL of liquid CD medium (NaNO3, 3 g; K2HPO3, 1 g; MgSO4.7H2O, 0.5 g; KCl, 0.5 g; FeSO4, 0.01 g; sucrose, 30 g; and deionized water to a total volume of 1000 mL). All flasks were incubated under constant shaking (150 × g) at 25 ℃ for 10 days.
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               Factor Part Location NP Content
 
CD medium (Filtrate extract)
 NA Changbai Mountain, China
NP Content: 1.990 ± 0.050 mg/mL
 
CD medium (20℃ + 3 days + PH5 + Medium volume: 25ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.0312 ± 0.0071 mg/mL
 
CD medium (20℃ + 7 days + PH6 + Medium volume: 50ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.0128 ± 0.0069 mg/mL
 
CD medium (20℃ + 11 days + PH7 + Medium volume: 100ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.1833 ± 0.0524 mg/mL
 
CD medium (20℃ + 15 days + PH8 + Medium volume: 150ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.3428 ± 0.2233 mg/mL
 
CD medium (25℃ + 15 days + PH5 + Medium volume: 50ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 2.0018 ± 0.0009 mg/mL
 
CD medium (25℃ + 11 days + PH6 + Medium volume: 25ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.8792 ± 0.0860 mg/mL
 
CD medium (25℃ + 7 days + PH7 + Medium volume: 150ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.4064 ± 0.1196 mg/mL
 
CD medium (25℃ + 3 days + PH8 + Medium volume: 100ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.2673 ± 0.0111 mg/mL
 
CD medium (30℃ + 7 days + PH5 + Medium volume: 100ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 1.0020 ± 0.0014 mg/mL
 
CD medium (30℃ + 3 days + PH6 + Medium volume: 150ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.3012 ± 0.1997 mg/mL
 
CD medium (30℃ + 15 days + PH7 + Medium volume: 25ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.3021 ± 0.2278 mg/mL
 
CD medium (30℃ + 11 days + PH8 + Medium volume: 50ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.4293 ± 0.2049 mg/mL
 
CD medium (35℃ + 11 days + PH5 + Medium volume: 150ml + Rotation speed: 150rpm)
 NA Changbai Mountain, China
NP Content: 1.2885 ± 0.1504 mg/mL
 
CD medium (35℃ + 15 days + PH6 + Medium volume: 100ml + Rotation speed: 100rpm)
 NA Changbai Mountain, China
NP Content: 1.2145 ± 0.1107 mg/mL
 
CD medium (35℃ + 3 days + PH7 + Medium volume: 50ml + Rotation speed: 250rpm)
 NA Changbai Mountain, China
NP Content: 0.8694 ± 0.0961 mg/mL
 
CD medium (35℃ + 7 days + PH8 + Medium volume: 25ml + Rotation speed: 200rpm)
 NA Changbai Mountain, China
NP Content: 1.0672 ± 0.0888 mg/mL
References
1 Fusarithioamide B, a new benzamide derivative from the endophytic fungus Fusarium chlamydosporium with potent cytotoxic and antimicrobial activities
2 Potential of the Endophytic Fungus Phialocephala fortinii Rac56 Found in Rhodiola Plants to Produce Salidroside and p-Tyrosol