Details of Natural Product (NP)

General Information of Natural Product (ID: NP1517)
  Natural Product Name
Indole-3-Carboxaldehyde
  Synonyms
INDOLE-3-CARBOXALDEHYDE; 1H-Indole-3-carbaldehyde; 487-89-8; 3-Formylindole; Indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde; Indole-3-aldehyde; 3-Indolecarboxaldehyde; INDOLE-3-CARBOXYALDEHYDE; Indol-3-carboxaldehyde; beta-Indolylaldehyde; 3-Indolecarbaldehyde; 3-Indolealdehyde; Indol-3-carbaldehyde; UNII-7FN04C32UO; MFCD00005622; NSC 10118; .beta.-Indolylaldehyde; 1H-indole-3-aldehyde; 7FN04C32UO; CHEMBL147741; Indole-3-carboxaldehyde (3-Formylindole); 3-Formylindol; 3-indolemethanal; Indol-3-carbaldehyd; 3-Formyl-1H-indole; EINECS 207-665-8; BRN 0114117; AI3-52407; b-Indolylaldehyde; 3-formyl indole; 3-formyl-indole; A-Indolylaldehyde; Indol-3-aldehyde; 3-indole aldehyde; indolyl-3-aldehyde; 3-indolylformaldehyde; 4877-89-8; indole-3-carboaldehyde; indole 3-carboxaldehyde; I3CHO; IIndole-3-carboxaldehyde; I3CA; 1H-indole-3-carbaldehyd; Indole-3- carboxaldehyde; h-indole-3-carboxaldehyde; indole-3-carboxy-aldehyde; 1H-Indole-3-carboxaldehde; bmse000645; SCHEMBL56373; 5-21-08-00246 (Beilstein Handbook Reference); Indole-3-carboxaldehyde, 97%; DTXSID5060069; CHEBI:28238; OLNJUISKUQQNIM-UHFFFAOYSA-; ZINC87959; ACN-S002805; ACT03589; BCP00081; NSC10118; AM1029; BDBM50182880; NSC-10118; STK387546; AKOS000119898; CS-W007376; HY-W007376; MCULE-6521465109; PS-5323; SB14957; NCGC00161738-01; NCGC00161738-02; AC-23425; DB-011568; BB 0242392; FT-0615872; FT-0652575; FT-0670335; I0027; 87I898; C08493; I-2200; AB00443651-03; Indole-3-carboxaldehyde, purum, >=98.0% (T); A827605; A871878; A897853; AG-205/01412034; CU-00000000108-1; Q27103575; F0918-0115; 1228547-52-1; 1H-indole-3-carbaldehyde1H-Indole-3-carboxaldehyde487-89-8246045-99-8.beta.-IndolylaldehydeIndole-3-carbaldehydeIndole-3-carboxaldehyde57210_FLUKA129445_ALDRICHZINC00087959SBB004120BAS 07339836C084933
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  Formula C9H7NO
  Weight 145.16
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C9H7NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-6,10H
  InChI Key OLNJUISKUQQNIM-UHFFFAOYSA-N
  Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C=O
  Canonical SMILES C1=CC=C2C(=C1)C(=CN2)C=O
  External Links PubChem ID 10256
CAS ID 487-89-8
NPASS ID NPC42372
CHEMBL ID CHEMBL147741
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Aeromicrobium sp. strain LGMB491
  Factor Name: SG medium [1]
              Species Info Factor Info
               Experiment Detail
V. divergens leaves with no marks or injuries were collected from 21 plants located in the Pantanal sul-mato-grossense/Brazil, specifically in two regions of the Pantanal of Miranda, Abobral (19° 30′ 09.5″ S, 57° 02′ 32.2″ W) and Sao Bento (19° 28′ 53.9″ S, 57° 02′ 36.9″ W). A large-scale fermentation (10 L) of strain LGMB491 was performed using SG culture medium at 36 ℃ for 10 days.
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               Factor Part Location NP Content
 
SG medium (36℃ + 10 days)
 Leaves Pantanal, Brazil
NP Content: 4.2 mg
      Species Name: Jishengella endophytica 161111
  Factor Name: Fermentation medium [2]
              Species Info Factor Info
               Experiment Detail
Jishengella endophytica 161111 was isolated and identified from the healthy roots of the mangrove plant, Xylocarpus granatum, collected from the mangrove reserve zone in Hainan Province, China. The spores of J. endophytica 161111 were directly cultured in 1000 mL Erlenmeyer flasks containing 200 mL fermentation media consisted of glucose 2%, yeast extract 0.5%, peptone 0.5%, KNO3 1.5%, CaCO3 0.4%, and NaCl 0.4% (pH 7.2). The cultures were incubated on a rotatory shaker at 220 rpm at 28 ℃ for 30 days.
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               Factor Part Location NP Content
 
Fermentation medium containing glucose 2%, yeast extract 0.5%, peptone 0.5%, KNO3 1.5%, CaCO3 0.4%, and NaCl 0.4% (28℃ + 30 days + PH7.2 + 220 rpm)
 Roots Hainan Province, China
NP Content: 3 mg
      Species Name: Microbispora sp. LGMB259
  Factor Name: R5A medium [3]
              Species Info Factor Info
               Experiment Detail
Strain LgMB259 was isolated by V. divergens leaves collected from the Pantanal, in the region of Nhecol ndia (S18° 10.07′, W57° 23.03′) in Brazil. The Microbispora sp. LGMB259 was cultivated on ISP3-agar plates at 37 ℃ for 7 days. Chunks of agar with the fully-grown strains were used to inoculate five (250 mL) Erlenmeyer flasks, each containing 50 mL of R5A medium . Individual cultures were grown at 37 ℃ for 3 days and subsequently used as seed cultures for the scale-up fermentation. The seed cultures were used to inoculate 80 Erlenmeyer flasks (250 mL) each containing 100 mL of R5A medium. Fermentation (8 L) was continued at 37 ℃ with, shaking (250 rpm) for 10 days.
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               Factor Part Location NP Content
 
R5A medium (37℃ + 10 days)
 Leaves Brazil
NP Content: 10.8 mg
References
1 Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil)
2 Alkaloids from the mangrove-derived actinomycete Jishengella endophytica 161111
3 Microbispora sp. LGMB259 endophytic actinomycete isolated from Vochysia divergens (Pantanal, Brazil) producing beta-carbolines and indoles with biological activity