Details of Natural Product (NP)

General Information of Natural Product (ID: NP1547)
  Natural Product Name
Calvasterol B
  Synonyms
Calvasterol B; (22e,24r)-9a,14a-dihydroxyergosta-4,7,22-trien-3,6-dione; 162857-86-5
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  Formula C28H40O4
  Weight 440.6
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C28H40O4/c1-17(2)18(3)7-8-19(4)21-10-12-27(31)24-16-23(30)22-15-20(29)9-11-25(22,5)28(24,32)14-13-26(21,27)6/h7-8,15-19,21,31-32H,9-14H2,1-6H3/b8-7+/t18-,19+,21+,25-,26+,27+,28+/m0/s1
  InChI Key PPPHAARYIMWGSU-VWLVVCIOSA-N
  Isomeric SMILES C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@]2([C@@]1(CC[C@]3(C2=CC(=O)C4=CC(=O)CC[C@@]43C)O)C)O
  Canonical SMILES CC(C)C(C)C=CC(C)C1CCC2(C1(CCC3(C2=CC(=O)C4=CC(=O)CCC43C)O)C)O
  External Links PubChem ID 11743978
CAS ID 162857-86-5

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Phomopsis sp. YM 355364
  Factor Name: PDB medium [1]
              Species Info Factor Info
               Experiment Detail
Fungal Material. The fungus was isolated from surface-sterilized fresh stems of an apparently healthy Aconitum carmichaeli collected in August 2008 in Huize County, Yunnan Province, P. R. China. The fungal strain was cultured on slants of PDA at 28 ℃ for 7 d. Then, the fresh mycelium was inoculated into 20x500-ml Erlenmeyer flasks each containing 120 ml of PDB medium (200 g potato and 20 g glucose in 1 l of H2O). After 4 d of the incubation at 28 ℃ on a rotary shaker at 200 r.p.m., a 20-ml culture liquid was transferred as seed into each of a total of 100 1-l Erlenmeyer flasks containing 250 ml of PDB medium. The following cultivation was kept for 7 d at 28 ℃ at 200 r.p.m. on a rotary shaker.
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               Factor Part Location NP Content
 
PDB medium (28℃ +7 days)
 Stems Huize County, Yunnan Province, China
NP Content: 15.2 mg
References
1 Two new steroids from an endophytic fungus Phomopsis sp