Details of Natural Product (NP)

General Information of Natural Product (ID: NP1599)
  Natural Product Name
Gibberellic Acid
  Synonyms
GIBBERELLIC ACID; Gibberellin A3; 77-06-5; Gibberellin; Berelex; Brellin; Gibberellin X; Gib-Tabs; Gibberellic acid GA3; Gib-Sol; Gibreskol; Cekugib; Grocel; Pro-Gibb; Pro-Gibb Plus; Gibberellins A4A7; Gibefol; Gibrescol; Regulex; Ryzup; Gibberellins; Gibberellinsaeure; (+)-Gibberellic Acid; Activol GA; Pgr-iv; Acide gibberellique; GA3; Gibberelic acid; UNII-BU0A7MWB6L; CHEBI:28833; Acide gibberellique [ISO-French]; NCI-C55823; MFCD00079329; BU0A7MWB6L; Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1alpha,2beta,4aalpha,4bbeta,10beta)-; Gibbrel; Gibberellic acid [BSI:ISO]; AI3-52922; (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid; NCGC00091033-01; DSSTox_CID_656; 2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone; DSSTox_RID_75715; Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone; DSSTox_GSID_20656; Gibberellate; (1alpha,2beta,4aalpha,4bbeta,10beta)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone; (3S,3aR,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propenoazuleno(1,2-b)furan-4-carboxylic acid; (3S,3aS,4S,4aS,6S,8aS,8bS,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid; (3S,3aS,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propeno(1,2-b)furan-4-carboxylic acid; 2beta,4aalpha,7-Trihydroxy-1beta-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone; 2beta,4alpha,7-Trihydroxy-1-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone; 2beta,4alpha,7-Trihydroxy-1-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone; GIBERELLIN; (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid; 2,4alpha,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10 beta-dicarboxylic acid 1,4alpha-lactone; Caswell No. 467; Gibberelate; Gibberelin; Gibberillate; GA [Plant Growth Regulator]; Gibberellic acid [ISO:BSI]; NSC14190; NSC19450; CCRIS 4820; Gibberillic acid; HSDB 712; Gibb-tabs; gibberellin 3; 4psb; 2,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-carboxylic acid 1-4-lactone; CAS-77-06-5; Gibberellin (GA); (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid; Gibb-3-ene-1, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1.alpha.,2.beta.,4a.alpha.,4b.beta.,10.beta.)-; EINECS 201-001-0; NSC 14190; EPA Pesticide Chemical Code 043801; GIBERILLIC ACID; BRN 0054346; Spectrum_000628; 4q0k; SpecPlus_000148; 2b-Hydroxygibberellin 1; GibberellinsA currencyure; PS49_SUPELCO; Prestwick0_000965; Prestwick1_000965; Prestwick2_000965; Prestwick3_000965; Spectrum2_000311; Spectrum3_001301; Spectrum4_001444; Spectrum5_000027; gibberellic acid (ga-3); bmse000317; SCHEMBL15577; BSPBio_000969; BSPBio_002961; KBioGR_001927; KBioSS_001108; 5-18-09-00269 (Beilstein Handbook Reference); MLS001055447; MLS002154076; DivK1c_006244; G7645_SIGMA; SPBio_000302; SPBio_002890; BPBio1_001067; MEGxm0_000440; GIBBERELLIC ACID, 90%; CHEMBL1232952; DTXSID0020656; ACon0_000224; ACon1_000551; BCBcMAP01_000012; KBio1_001188; KBio2_001108; KBio2_003676; KBio2_006244; KBio3_002181; HMS1571A11; HMS2098A11; HMS2231J16; HMS3039M06; HY-N1964; ZINC3860467; Tox21_202052; Tox21_303023; BDBM50561592; GEO-04261; MD-920; NSC-14190; NSC-19450; s4766; AKOS025310145; CCG-208472; DB07814; SMP1_000136; NCGC00091033-02; NCGC00091033-03; NCGC00091033-04; NCGC00091033-05; NCGC00091033-06; NCGC00091033-09; NCGC00256446-01; NCGC00259601-01; AS-14216; K339; NCI60_000922; SMR000686070; SMR001233386; AB00513979; CS-0018282; Gibberellic acid 100 microg/mL in Acetonitrile; Gibberellin, 80% gibberellin A3 basis (TLC); 079G329; Q411138; Gibberellic acid, 90% gibberellin A3 basis (HPLC); Gibberellic acid, PESTANAL(R), analytical standard; BRD-K92758126-001-05-5; BRD-K92758126-001-06-3; BRD-K92758126-001-17-0; 6F94D8A8-3230-4AB5-93C1-46F5E84FE343; Gibberellic acid, United States Pharmacopeia (USP) Reference Standard; Gibberellic Acid, Pharmaceutical Secondary Standard; Certified Reference Material; (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-Dihydroxy-11-methyl-6-methylene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-13-ene-9-carboxylic acid; (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1(5,8).0(1,10).0(2,8)]heptadec-13-ene-9-carboxylic acid; (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid; 10365-11-4; 2beta,7alpha-dihydroxy-1beta-methyl-8-methylidene-13-oxo-4a,1alpha-epoxymethano-4aalpha,4bbeta-gibb-3-ene-10beta-carboxylic acid; Gibberellic acid, plant cell culture tested, BioReagent, >=90% gibberellin A3 basis (of total gibberellins.)
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  Formula C19H22O6
  Weight 346.4
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10-,11+,12-,13-,16-,17+,18+,19-/m1/s1
  InChI Key IXORZMNAPKEEDV-OBDJNFEBSA-N
  Isomeric SMILES C[C@@]12[C@H](C=C[C@@]3([C@@H]1[C@@H]([C@]45[C@H]3CC[C@](C4)(C(=C)C5)O)C(=O)O)OC2=O)O
  Canonical SMILES CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O
  External Links PubChem ID 6466
CAS ID 1977-06-05
NPASS ID NPC9848
CHEMBL ID CHEMBL1232952
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Streptomyces collinus strain SP8
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 6.14 ± 0.45 µg/ml
      Species Name: Streptomyces diastaticus strain SP2
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 7.02 ± 0.24 µg/ml
      Species Name: Streptomyces fradiae strain SP4
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 5.74 ± 0.72 µg/ml
      Species Name: Streptomyces griseus strain SP12
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 8.13 ± 0.61 µg/ml
      Species Name: Streptomyces olivochromogenes strain SP5
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 6.01 ± 0.13 µg/ml
      Species Name: Streptomyces ossamyceticus strain SP10
  Factor Name: Raulin-Thom medium [1]
              Species Info Factor Info
               Experiment Detail
Healthy medicinal plants were collected from CSIR-National Botanical Research Institute (Banthara) (26° 55′ N, 80° 59′ E), Lucknow, India during June, 2013. Catechol type and hydroxamate siderophores were estimated by Arnow's method (Arnow 1937) and Csaky test (Csaky 1948) respectively. The amount of IAA produced by Actinomycetes isolates was determined using GYM broth supplemented with different concentration of l-tryptophan (Basal, 0, 2 and 5 mg/ml) and incubated at 30 ℃ with shaking at 125 rev/min for 7 days (Gordon and Weber 1951). Appearance of a pink colour indicated IAA production. The level of IAA produced was estimated by comparison with an IAA standard. Gibberellic acid (GA3) production was determined according to Borrow et al. (1955)(In submerged aerated culture on Raulin-Thom medium (4% sucrose) in 18 days at 25 ℃.).
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               Factor Part Location NP Content
 
Raulin-Thom medium (25℃ + 18 days)
 Roots Lucknow, India
NP Content: 4.66 ± 0.24 µg/ml
References
1 Evaluation of antagonistic and plant growth promoting activities of chitinolytic endophytic actinomycetes associated with medicinal plants against Sclerotium rolfsii in chickpea