Details of Natural Product (NP)

General Information of Natural Product (ID: NP1671)
  Natural Product Name
2-(D-Alanylamino)-N-[(1S)-1-Hydroxy-3-Mercaptopropyl]Benzamide
  Synonyms
fusarithioamide A; CHEMBL4576097; CHEBI:141359; 2-(D-alanylamino)-N-[(1S)-1-hydroxy-3-mercaptopropyl]benzamide; 2-(D-alanylamino)-N-[(1S)-1-hydroxy-3-sulfanylpropyl]benzamide
Click to Show/Hide
  Formula C13H19N3O3S
  Weight 297.38
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C13H19N3O3S/c1-8(14)12(18)15-10-5-3-2-4-9(10)13(19)16-11(17)6-7-20/h2-5,8,11,17,20H,6-7,14H2,1H3,(H,15,18)(H,16,19)/t8-,11+/m1/s1
  InChI Key DQGIXJCPVVNGMY-KCJUWKMLSA-N
  Isomeric SMILES C[C@H](C(=O)NC1=CC=CC=C1C(=O)N[C@H](CCS)O)N
  Canonical SMILES CC(C(=O)NC1=CC=CC=C1C(=O)NC(CCS)O)N
  External Links PubChem ID 134692099
CHEMBL ID CHEMBL4576097
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Fusarium chlamydosporium
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
In March 2013, Anvillea garcinii (Burm.f.) DC. (Asteraceae) was obtained from the wildly growing plant at Al-Azhar University campus. A sample from preserved fungus (FuC/March 2013) was cultivated on solid rice cultures (10 Erlenmeyer flasks × 1L). The cultures were incubated at room temperature under a septic condition for 30 days.
Click to Show/Hide
               Factor Part Location NP Content
 
Solid rice medium (25℃ + 30 days)
 Leaves inner tissues Al-Azhar University, Cairo, Egypt
NP Content: 7.9 mg
      Species Name: Fusarium chlamydosporum
  Factor Name: Rice Medium [2]
              Species Info Factor Info
               Experiment Detail
Anvillea garcinii (Burm.f.) DC. (Asteraceae) was collected in March 2013 from the plant wildly growing at campus of Al-Azhar University. The fresh culture was transmitted into rice solid cultures (15 Erlenmeyer flasks, 1L each). The cultures have been incubated under septic conditions for 30 days at room temperature.
Click to Show/Hide
               Factor Part Location NP Content
 
Rice Medium (25 degrees Celsius + 30Days)
 leaves Al-Azhar University, Assiut Branch, Assiut, Egypt
NP Content: 5.6 mg
References
1 Fusarithioamide B, a new benzamide derivative from the endophytic fungus Fusarium chlamydosporium with potent cytotoxic and antimicrobial activities
2 Fusarithioamide A, a new antimicrobial and cytotoxic benzamide derivative from the endophytic fungus Fusarium chlamydosporium