The fresh bark of Ilex cornuta was obtained from the suburb of Nanjing, Jiangsu, People's Republic of China, in May 2012. P. glomerata was cultivated on PDA for five days, and 32 pieces of the agar were added into eight Erlenmeyer flasks (500 mL) each containing 100 mL of potato dextrose liquid medium. The cultures were incubated using a rotatory shaker at 28 ℃ and 120 rpm for seven days to prepare the seed culture. Solid fermentation was carried out in 50 Erlenmeyer flasks (500 mL) each containing 100 g of rice and 150 mL of water, which were sterilized at 115 ℃ for 30 min. After being incubated with 20 mL of seed culture, the flasks were cultivated at 28 ℃ for 30 days.