Details of Natural Product (NP)

General Information of Natural Product (ID: NP1847)
  Natural Product Name
Penicisulfuranol A
  Synonyms
Penicisulfuranol A; CHEMBL4074794
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  Formula C21H21ClN2O8S2
  Weight 529
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C21H21ClN2O8S2/c1-23-17(26)20-8-19(28)12(22)7-5-10(25)15(19)32-24(20)18(27)21(23)16(33-34-20)9-4-6-11(29-2)14(30-3)13(9)31-21/h4-7,10,12,15-16,25,28H,8H2,1-3H3/t10-,12-,15+,16-,19+,20-,21+/m1/s1
  InChI Key HFWZFFCNOVVKQT-OFDQUPMBSA-N
  Isomeric SMILES CN1C(=O)[C@]23C[C@@]4([C@@H](C=C[C@H]([C@@H]4ON2C(=O)[C@@]15[C@@H](C6=C(O5)C(=C(C=C6)OC)OC)SS3)O)Cl)O
  Canonical SMILES CN1C(=O)C23CC4(C(C=CC(C4ON2C(=O)C15C(C6=C(O5)C(=C(C=C6)OC)OC)SS3)O)Cl)O
  External Links PubChem ID 137650848
CHEMBL ID CHEMBL4074794
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Penicillium janthinellum HDN13-309
  Factor Name: Liquid medium [1]
              Species Info Factor Info
               Experiment Detail
The mangrove plant Sonneratia caseolaris was collected from Hainan Province in 2012. The fungus P. janthinellum HDN13-309 was cultured under static conditions at 28 ℃ in 1000 mL Erlenmeyer flasks containing 300 mL of liquid medium containing maltose (2%), mannitol (2%), glucose (1%), sodium glutamate (1%), yeast extract (0.3%), corn syrup (0.1%), KH2PO4 (0.05%), and MgSO4.7H2O (0.03%) dissolved in naturally collected seawater (Huiquan Bay, Yellow Sea, Qiangdao, China). After 4 weeks of cultivation, the whole broth (20 L) was filtered through cheesecloth to separate supernatant and mycelia.
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               Factor Part Location NP Content
 
Liquid medium containing maltose (2%), mannitol (2%), glucose (1%), sodium glutamate (1%), yeast extract (0.3%), corn syrup (0.1%), KH2PO4 (0.05%), and MgSO4.7H2O (0.03%) (28℃ + 28 days)
 Roots Hainan Province, China
NP Content: 20 mg
References
1 Penicisulfuranols A-F, Alkaloids from the Mangrove Endophytic Fungus Penicillium janthinellum HDN13-309