Details of Natural Product (NP)

General Information of Natural Product (ID: NP1992)
  Natural Product Name
Curvularin
  Synonyms
Curvularin|10140-70-2|UNII-WT39K5T3BX|WT39K5T3BX|(5S)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),13,15-triene-3,11-dione|2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-|2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (4S)-|(-)-Curvularin|NSC 166071|CHEMBL478770|SCHEMBL15256930|DTXSID001017585|HY-N6770|ZINC1649222|(4S)-4,5,6,7,8,9-Hexahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione|BC162716|CS-0034951|Curvularin, from Penicillium citrinum, >=98% (HPLC)|(S)-11,13-dihydroxy-4-methyl-4,5,6,7,8,9-hexaydro-1H-benzo[d][1]oxacyclododecine-2,10-dione
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  Formula C16H20O5
  Weight 292.33
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C16H20O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h7,9-10,17,19H,2-6,8H2,1H3/t10-/m0/s1
  InChI Key VDUIGYAPSXCJFC-JTQLQIEISA-N
  Isomeric SMILES C[C@H]1CCCCCC(=O)C2=C(CC(=O)O1)C=C(C=C2O)O
  Canonical SMILES CC1CCCCCC(=O)C2=C(CC(=O)O1)C=C(C=C2O)O
  External Links PubChem ID 119418
CAS ID 10140-70-2
NPASS ID NPC178467
CHEMBL ID CHEMBL478770
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Curvularia sp. M12
  Factor Name: Rice Medium [1]
              Species Info Factor Info
               Experiment Detail
The healthy leaves of the curry plant (Murraya koenigii) were collected from the garden of medicinal plants, Department of Pharmacy, Rajshahi University, Bangladesh. The fungal strain M12 was subcultured on M2 agar medium and incubated at 25 °C for 3 days. Rice (200 g) and tap water (130 mL) were added into each of 24 P-flasks and then sterilized (121 °C for 15 min). The P-flasks were inoculated with well-grown agar cultures of the strain M12 (pieces 1 × 1 cm) and incubated at 30 °C for 25 days.
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               Factor Part Location NP Content
 
Rice Medium (30 degrees Celsius + 25Days)
 leaves Rajshahi University, Bangladesh
NP Content: 16 mg
References
1 Metabolites from the Endophytic Fungus Curvularia sp. M12 Act as Motility Inhibitors against Phytophthora capsici Zoospores