Details of Natural Product (NP)

General Information of Natural Product (ID: NP2007)
Natural Product Name	Modiolide A
Synonyms	Modiolide A\|5,8-dihydroxy-10-methyl-5,8,9,10-tetrahydro-2H-oxecin-2-one\|CHEMBL517659\|SCHEMBL15516225\|CHEBI:190592\|ZINC14594569\|(2R,4S,5E,7R,8Z)-4,7-dihydroxy-2-methyl-2,3,4,7-tetrahydrooxecin-10-one Click to Show/Hide
Formula	C₁₀H₁₄O₄
Weight	198.22
Structure
Structure	3D Structure Download		2D Structure Download
InChI	InChI=1S/C10H14O4/c1-7-6-9(12)3-2-8(11)4-5-10(13)14-7/h2-5,7-9,11-12H,6H2,1H3/b3-2+,5-4-/t7-,8-,9-/m1/s1
InChI Key	MKPZLFSGCUYQEY-JKPBTABPSA-N
Isomeric SMILES	C[C@@H]1C[C@@H](/C=C/[C@H](/C=C\\C(=O)O1)O)O
Canonical SMILES	CC1CC(C=CC(C=CC(=O)O1)O)O
External Links	PubChem ID	643697
	NPASS ID	NPC97570
	CHEMBL ID	CHEMBL517659
NP Activity Charts	Click to show/hide
Activity Info

The Content Variation of Natural Product Induced by Different Factor(s)
*Species Name: Curvularia* sp. M12**
	Factor Name: Rice Medium				[1]
Species Info Factor Info
Experiment Detail		The healthy leaves of the curry plant (Murraya koenigii) were collected from the garden of medicinal plants, Department of Pharmacy, Rajshahi University, Bangladesh. The fungal strain M12 was subcultured on M2 agar medium and incubated at 25 °C for 3 days. Rice (200 g) and tap water (130 mL) were added into each of 24 P-flasks and then sterilized (121 °C for 15 min). The P-flasks were inoculated with well-grown agar cultures of the strain M12 (pieces 1 × 1 cm) and incubated at 30 °C for 25 days. Click to Show/Hide
Factor			Part	Location		NP Content
Rice Medium (30 degrees Celsius + 25Days)			leaves	Rajshahi University, Bangladesh		NP Content: 13.3 mg

References
1	Metabolites from the Endophytic Fungus Curvularia sp. M12 Act as Motility Inhibitors against Phytophthora capsici Zoospores