Details of Natural Product (NP)

General Information of Natural Product (ID: NP2046)
  Natural Product Name
Chaetoglobosin U
  Synonyms
Chaetoglobosin U|CHEBI:68733|CHEMBL448756|Q27137152|(3aR,5aR,8S,8aR,9S,9aR,10aS,10bR,11E,14S,14aR)-2-hydroxy-8-(1H-indol-3-ylmethyl)-1,9,9a,14-tetramethyl-3a,4,7,8,8a,9,9a,10a,10b,13,14,14a-dodecahydro-3H-cyclopenta[7,8]cyclodeca[1,2-d]oxireno[f]isoindole-3,5,6-trione
Click to Show/Hide
  Formula C32H36N2O5
  Weight 528.6
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C32H36N2O5/c1-15-8-7-10-21-29-31(4,39-29)17(3)26-23(12-18-14-33-22-11-6-5-9-19(18)22)34-30(38)32(21,26)24(35)13-20-25(15)16(2)27(36)28(20)37/h5-7,9-11,14-15,17,20-21,23,25-26,29,33,36H,8,12-13H2,1-4H3,(H,34,38)/b10-7+/t15-,17-,20+,21-,23-,25-,26-,29-,31+,32+/m0/s1
  InChI Key MRENMDHAGXAXRK-QFHPAQOTSA-N
  Isomeric SMILES C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2(C(=O)C[C@@H]5[C@@H]1C(=C(C5=O)O)C)C(=O)N[C@H]4CC6=CNC7=CC=CC=C76)C)C
  Canonical SMILES CC1CC=CC2C3C(O3)(C(C4C2(C(=O)CC5C1C(=C(C5=O)O)C)C(=O)NC4CC6=CNC7=CC=CC=C76)C)C
  External Links PubChem ID 11570022
NPASS ID NPC290529
CHEMBL ID CHEMBL448756
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Chaetomium globosum TY-2
  Factor Name: Oatmeal Medium [1]
              Species Info Factor Info
               Experiment Detail
A strain of C. globosum TY-2 was initially isolated from the plant Polygonatum sibiricum, collected in 2015 from Linan, Zhejiang Province, China. Serial transfers of one of the resulting colonies from Polygonatum sibiricum provided a pure strain of C. globosum. The fungal strain was cultured at 28 &#8451 for six weeks in a oatmeal medium (50 L) containing 1 % soluble sucrose and 0.1 % casein.
Click to Show/Hide
               Factor Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
 NA Linan, Zhejiang Province, China
NP Content: 0.9 mg
References
1 Identification of a Unique Azaphilone Produced by Chaetomium globosum Isolated from Polygonatum sibiricum