Details of Factor

General Information of Factor (ID: FP130)
  Factor Name Oatmeal Medium
  Factor Type Environmental Conditions
  Factor Description
Each microbial strain has the potential to produce multiple compounds, but only subsets of these compounds are made under specific growth conditions. Therefore, variations in cultivation parameters can elicit the production and discovery of new secondary metabolites by changing cultivation parameters such as media composition, various nutrients, trace elements, physical parameters (i.e., pH, temperature), and chemical elicitors (i.e., sub-lethal concentrations of antibiotics, communication molecules). Moreover, the co-cultivation of microbes and the addition of factors affecting epigenetic control can also be framed within the OSMAC principle.
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 The Content Variation of Natural Product Induced by This Factor
      Species Name: Chaetomium globosum TY-2
          Species Info Click to show the detail information of this Factor
          Experiment Detail
A strain of C. globosum TY-2 was initially isolated from the plant Polygonatum sibiricum, collected in 2015 from Linan, Zhejiang Province, China. Serial transfers of one of the resulting colonies from Polygonatum sibiricum provided a pure strain of C. globosum. The fungal strain was cultured at 28 &#8451 for six weeks in a oatmeal medium (50 L) containing 1 % soluble sucrose and 0.1 % casein.
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            (1R,7Z,9S,11Z,13R,14S,16R,17S,18R,19S)-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-7,11-diene-2,5,6,21-tetrone [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 2.1 mg
            Chaephilone A [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 4.8 mg
            Chaephilone E [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 5.2 mg
            Chaetoglobin B [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 4.4 mg
            Chaetoglobosin A [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 3.6 mg
            Chaetoglobosin U [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 0.9 mg
            Chaetomugilide A [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 3.9 mg
            Chaetomugilin A [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 1.9 mg
            Chaetomugilin I [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 15.1 mg
            Chaetomugilin J [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 2.8 mg
            Chaetomugilin Q [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 5.6 mg
            Chaetoviridin G [1]
               Factor Link Part Location NP Content
 
Oatmeal Medium with 1 % soluble sucrose and 0.1 % casein (28 degrees Celsius + 42Days)
    NP Info    NA Linan, Zhejiang Province, China
NP Content: 6.2 mg

References
1 Identification of a Unique Azaphilone Produced by Chaetomium globosum Isolated from Polygonatum sibiricum