Actinomycete strain BCC72023 was isolated in a stem of rice (O. sativa L.) collected from the Chumphon province, Thailand. Streptomyces sp. BCC72023 was grown on ISP-2 agar at 30 &#8451 for 7 days and then the agar was cut into pieces. The pieces were inoculated into 250 ml Erlenmeyer flasks, which each contained 100 ml of ISP2 medium, for 7 days at 30 &#8451 on a rotary shaker (200 rpm). Then the seed culture (20 flasks) was transferred into 80 × 1 l Erlenmeyer flasks, which each contained 250 ml of ISP2 medium. The production culture (20 l) was cultivated for 14 days at 30 &#8451 on rotary shakers (200 rpm).