General Information of Species (ID: SP0127)
  Species Name
Crocus sativus
  Species Genus Crocus
  Species Family Iridaceae
  Studied Organism Crocus sativus L.
  External Links
Taxonomy ID 82528
CMAUP ID NPO9445
NPASS ID NPO9445

 The Content Variation of Natural Product Induced by Different Factor(s)
      Locality Variation; Plant Pathogen Infection [1]
              Factor Info Click to show the detail information of this Factor
               Experiment Detail
Several surveys were carried out during the growing seasons 2014-2016 in major C. sativus cultivation areas of Iran with different environmental conditions, including Tehran, Fars, Isfahan, Kerman, and Razavi Khorasan provinces. C. sativus corms were randomly collected and tested for virus infections and planted in an experimental field located in the University of Tehran, Karaj, Iran.Based on the serological results, 44 saffron samples testing positive for the presence of potyviruses and 16 saffron samples that were free of viruses were selected for further analysis.Stigma tissues of SaLV-infected and uninfected samples were snap frozen in liquid nitrogen and dried using Zirbus VaCo 5 Laboratory Freeze Dryer (ZIRBUS technology GmbH, Bad Grund/Harz, Germany) under pressure of 0.02 mbar for 48 h and were kept in -80℃.
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               Factor Function
Saffron plants grown at various conditions (considering altitude, temperature, and precipitation/rainfall) and in presence/absence of virus infections; we found that edaphoclimatic and cultivation conditions significantly determine the quality of the spice and the presence of virus modifies the content of its metabolites.
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   (Locality: Isfahan province, Iran) + (Positive of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 3.02 ± 1.90 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 44.15 ± 26.21 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 40.80 ± 22.13 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 4.13 ± 2.29 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 149.91 ± 91.82 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 1.00 ± 0.88 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.68 ± 2.45 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.72 ± 2.16 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 1.19 ± 0.94 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content: 0.47 ± 0.20 mg/g
 
Total Crocins
   NP Info                 NA         NA
NP Content: 128.36 ± 68.54 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.70 ± 1.52 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 0.95 ± 0.51 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 9.84 ± 5.75 mg/g
   (Locality: Isfahan province, Iran) + (Negative of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 3.19 ± 0.79 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 51.73 ± 6.50 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 48.38 ± 4.79 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 6.29 ± 2.61 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 151.96 ± 26.56 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 1.11 ± 1.01 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.75 ± 1.00 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 4.67 ± 0.96 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 1.71 ± 0.86 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 152.70 ± 15.31 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.84 ± 0.34 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.16 ± 0.20 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 11.85 ± 2.35 mg/g
   (Locality: Razavi Khorasan province, Iran) + (Positive of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 2.95 ± 2.03 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 51.11 ± 35.07 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 31.94 ± 16.67 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 2.76 ± 1.96 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 109.68 ± 70.19 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 1.75 ± 2.05 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.57 ± 1.91 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 7.06 ± 6.28 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 1.32 ± 0.94 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 114.87 ± 64.43 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.96 ± 1.20 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.22 ± 0.80 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 5.11 ± 3.10 mg/g
   (Locality: Razavi Khorasan province, Iran) + (Negative of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 4.16 ± 2.21 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 71.63 ± 27.32 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 46.47 ± 3.54 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 4.99 ± 2.54 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 171.68 ± 1 3.54 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 3.74 ± 3.17 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.78 ± 0.63 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 4.73 ± 7.38 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 2.04 ± 0.10 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 164.42 ± 27.71 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.96 ± 0.56 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.45 ± 0.57 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 8.01 ± 4.14 mg/g
   (Locality: Tehran province, Iran) + (Positive of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 3.05 ± 0.58 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 58.95 ± 16.13 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 44.81 ± 7.40 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 5.41 ± 1.69 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 138.08 ± 3 8.24 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 0.59 ± 0.39 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.26 ± 0.90 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 11.49 ± 2.04 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 2.11 ± 0.66 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 144.33 ± 26.61 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.06 ± 0.76 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.42 ± 0.57 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 9.72 ± 2.33 mg/g
   (Locality: Tehran province, Iran) + (Negative of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 3.16 ± 0.24 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 61.58 ± 4.38 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 43.47 ± 4.71 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 5.56 ± 1.03 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 115.43 ± 58.93 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 0.53 ± 0.62 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.75 ± 1.99 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 14.65 ± 0.43 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 2.21 ± 0.12 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 152.50 ± 13.25 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 5.58 ± 3.22 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.56 ± 0.12 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 8.37 ± 1.84 mg/g
   (Locality: Fars province, Iran) + (Positive of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 4.83 ± 1.66 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 54.16 ± 11.96 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 50.42 ± 7.59 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 6.68 ± 1.35 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 95.02 ± 28.44 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: < LOQ mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 4.59 ± 1.89 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 12.64 ± 1.86 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 1.07 ± 0.83 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 155.44 ± 21.03 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.62 ± 2.50 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.46 ± 0.30 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 13.30 ± 3.31 mg/g
   (Locality: Fars province, Iran) + (Negative of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 4.02 ± 1.12 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 61.17 ± 7.12 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 44.46 ± 9.65 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 4.78 ± 1.19 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 32.98 ± 5.36 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: < LOQ mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 4.22 ± 1.50 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 12.24 ± 1.74 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 0.77 ± 0.61 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 149.75 ± 24.43 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.24 ± 0.40 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.31 ± 0.09 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 10.46 ± 4.14 mg/g
   (Locality: Kerman province, Iran) + (Positive of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 4.65 ± 1.79 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 77.95 ± 21.94 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 46.68 ± 11.22 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 2.00 ± 0.88 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 51.86 ± 9.58 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 0.78 ± 1.25 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.28 ± 0.69 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.32 ± 1.56 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 1.03 ± 0.68 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 159.35 ± 37.39 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 3.09 ± 0.98 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.77 ± 0.52 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 6.68 ± 2.33 mg/g
   (Locality: Kerman province, Iran) + (Negative of Saffron latent virus infection)    ( Part: Stigma tissues; Location: Karaj, Iran )
               NP Name Link Formula PubChem ID NP Content
 
Crocetin Neapolitanose Gentiobiosyl Ester
   NP Info                 C50H74O29         25246046  
NP Content: 5.17 ± 2.50 mg/g
 
Crocin
   NP Info                 C44H64O24         5281233  
NP Content: 77.73 ± 15.31 mg/g
 
Crocetin Gentiobiosylglucosyl Ester
   NP Info                 C38H54O19         9940690  
NP Content: 46.72 ± 4.48 mg/g
 
Beta-D-Glucosyl Crocetin
   NP Info                 C26H34O9         10368299  
NP Content: 2.60 ± 0.89 mg/g
 
Picrocrocin
   NP Info                 C16H26O7         130796  
NP Content: 94.19 ± 47.15 mg/g
 
Safranal
   NP Info                 C10H14O         61041  
NP Content: 2.65 ± 3.48 mg/g
 
Cis-Crocetin (Beta-D-Glucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.78 ± 0.80 mg/g
 
Cis-Crocetin Di-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 2.99 ± 1.60 mg/g
 
Kaempferol 3-O-Sophoroside-7-O-Glucoside
   NP Info                 NA         NA
NP Content: 0.69 ± 0.83 mg/g
 
Kaempferol Tetrahexoside
   NP Info                 NA         NA
NP Content:
 
Total Crocins
   NP Info                 NA         NA
NP Content: 161.12 ± 19.95 mg/g
 
Trans-Crocetin (Beta-D-Neapolitanosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.28 ± 0.61 mg/g
 
Trans-Crocetin (Beta-D-Triglucosyl)-(Beta-D-Gentiobiosyl) Ester
   NP Info                 NA         NA
NP Content: 1.58 ± 0.51 mg/g
 
Trans-Crocetin Di-(Beta-D-Glucosyl) Ester
   NP Info                 NA         NA
NP Content: 7.03 ± 2.18 mg/g
References
1 The effects of geographical origin and virus infection on the saffron (Crocus sativus L.) quality