General Information of Species (ID: SP0245)
  Species Name
Micromonospora fiedleri
  Species Genus Micromonospora
  Species Family Micromonosporaceae
  Microbe Type Marine-Derived Actinomycetes
  Studied Organism Verrucosispora strain MG-37
  External Links
Taxonomy ID 1157498
Genbank ID NR_109601

 The Content Variation of Natural Product Induced by Different Factor(s)
      Fermentation medium [1]
              Factor Info Click to show the detail information of this Factor
               Experiment Detail
Strain MG-37 was isolated from sediment collected by us (ATB, GK) in the Raune Fjord, Norway (N 60° 15.898, E 5° 08.237) at a depth of 250 meters. Strain MG-37 was cultivated in a 10-liter stirred tank fermentor (Biostat S, B. Braun Melsungen, Germany) in a complex medium that consisted of soluble starch 10 g, glucose 10 g, glycerol 10 g, cornsteep powder (Marcor) 2.5 g, Bacto peptone 5.0 g, yeast extract (Ohly Kat) 2.0 g, NaCl 1.0 g and CaCO3 3.0 g in 1.0 liter tap water, adjusted to pH 7.3 prior to sterilization. The fermentor was inoculated with 5 vol-% of shake cultures, grown in 500-ml Erlenmeyer flasks with one baffle for 48 hours on a rotary shaker at 120 rpm and 27 ℃ using the same medium. The fermentation was carried out for 96 hours at 27 ℃ with an aeration rate of 0.5 liter/liter culture/minute and an agitation of 250 rpm.
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  Fermentation medium containing soluble starch 10 g, glucose 10 g, glycerol 10 g, cornsteep powder 2.5 g, Bacto peptone 5.0 g, yeast extract 2.0 g, NaCl 1.0 g and CaCO3 3.0 g (27℃ + 4 days + PH7.3 + 250 rpm)   (Part: .; Location: Raune Fjord, Norway)
               NP Name Link Host Plant Part Location NP Content
 
Proximicin C
NP Info . NA Raune Fjord, Norway
NP Content: 12 mg/L
 
Proximicin B
NP Info . NA Raune Fjord, Norway
NP Content: 13 mg/L
 
Proximicin A
NP Info . NA Raune Fjord, Norway
NP Content: 3 mg/L
References
1 Proximicin A, B and C, novel aminofuran antibiotic and anticancer compounds isolated from marine strains of the actinomycete Verrucosispora