Details of Natural Product (NP)

General Information of Natural Product (ID: NP1704)
  Natural Product Name
Cyschalasin A
  Synonyms
Cyschalasin A; CHEMBL4537893
Click to Show/Hide
  Formula C28H42N2O5S
  Weight 518.7
  Structure Could Not Find 2D Structure
3D Structure Download 2D Structure Download
  InChI InChI=1S/C28H42N2O5S/c1-15(2)11-21-25-18(5)17(4)13-20-12-16(3)7-8-22(32)23(33)14-24(36-10-9-29-19(6)31)26(34)28(20,25)27(35)30-21/h12-13,15,18,20-22,24-25,32H,7-11,14H2,1-6H3,(H,29,31)(H,30,35)/b16-12+/t18-,20+,21+,22-,24-,25+,28+/m1/s1
  InChI Key XEUIJZSFKASMIJ-HBBZWIBTSA-N
  Isomeric SMILES C[C@H]1[C@H]2[C@@H](NC(=O)[C@@]23[C@@H](/C=C(/CC[C@H](C(=O)C[C@H](C3=O)SCCNC(=O)C)O)\\C)C=C1C)CC(C)C
  Canonical SMILES CC1C2C(NC(=O)C23C(C=C(CCC(C(=O)CC(C3=O)SCCNC(=O)C)O)C)C=C1C)CC(C)C
  External Links PubChem ID 145721091
CHEMBL ID CHEMBL4537893
  NP Activity Charts   Click to show/hide
  Activity Info  

 The Content Variation of Natural Product Induced by Different Factor(s)
      Species Name: Aspergillus neoflavipes
  Factor Name: Rice medium [1]
              Species Info Factor Info
               Experiment Detail
The fungus Aspergillus micronesiensis was isolated from the root of the traditional Chinese medicinal plant Phyllanthus glaucus, collected from LuShan Mountain, Jiangxi Province, China (2015). The strain was cultured on potato dextrose agar (PDA) for 5 days to prepare the seed culture. Agar plugs were inoculated into 150 sterilized Erlenmeyer flasks (1 L), each containing 200 g of rice and 200 mL of water. All flasks were incubated at 25 ℃ for 5 weeks.
Click to Show/Hide
               Factor Part Location NP Content
 
Rice medium (25℃ + 35 days)
 Roots LuShan Mountain, Jiangxi Province, China
NP Content: 4.7 mg
References
1 Cysteine Residue Containing Merocytochalasans and 17,18- seco-Aspochalasins from Aspergillus micronesiensis